Expression quantitative trait locus mapping in recombinant gametes using single nucleus RNA sequencing
Matthew T. Parker,
Samija Amar,
José A. Campoy
et al.
Abstract:Phenotypic differences between individuals of a species are often caused by differences in gene expression, which are in turn caused by genetic variation. Expression quantitative trait locus (eQTL) analysis is a methodology by which we can identify such causal variants. Scaling eQTL analysis is costly due to the expense of generating mapping populations, and the collection of matched transcriptomic and genomic information. We developed a rapid eQTL analysis approach using single-cell/nucleus RNA sequencing of … Show more
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