Scramjet propulsion is a promising technology that could lead to substantial improvements in cost and flexibility for access to space for satellite placement into Low Earth Orbit. However, scramjet development is hindered by different technological issues. Amongst these, fast and efficient fuel-air mixing, and heat management, are key areas. By increasing mixing rate, the combustor can be shortened while keeping a high combustion efficiency. This reduces drag and heat losses, highly improving the feasibility and viability of scramjet engine designs. Several techniques have been proposed to increase mixing rate in scramjets, such as hypermixers and strut injectors. However, these techniques improve mixing at the expense of increased losses and local heat loads.For this reason, the use of naturally occurring vortices in scramjet flowfields for mixing enhancement came into consideration. Most scramjet geometries inherently generate streamwise vortices. Therefore, there are no increased losses when using these vortices for mixing enhancement. However, these vortices are weaker than those generated by hypermixers or struts.Hence, the ability of these vortices to effectively enhance mixing rate has to be evaluated.This work addresses the study of the interaction between streamwise vortices in scramjet flowfields and fuel injected through an inclined porthole injector to establish optimum arrangements for scramjet performance. The analysis of this interaction is performed numerically and experimentally. Numerical RANS simulations are used as the principal tool to analyse and describe the vortex-injection interaction. In addition, experimental data was gathered to assess the validity of the numerical approach. Scramjet flows are highly complex. To study the effect of the vortex in isolation, a simplified, canonical geometry, consisting of a flat plate with a normal fin is used. The swept shock generated by the fin interacts with the flat plate boundary layer, inducing the formation of a vortex. The features of this vortex are equivalent to those of vortices present in real scramjet flowfields. Moreover, this geometry allows to control the vortex intensity by modifying the fin compression angle. The flat plate incorporates a porthole injector, from which Hydrogen fuel is injected into the vortex. The interaction between the injected fuel and the streamwise vortex was studied focusing on its effect on mixing. Moreover, its effects on maximum wall heat flux, and fuel combustion were also analysed.