A method is presented for 3D MRI in an extended field of view (FOV) based on continuous motion of the patient table and an efficient acquisition scheme. A gradient-echo MR pulse sequence is applied with lateral (left-right (L/R)) frequency-encoding direction and slab selection along the direction of motion. Compensation for the table motion is achieved by a combination of slab tracking and data alignment in hybrid space. The method allows fast k-space coverage to be achieved, especially when a short sampling FOV is chosen along the direction of table motion, as is desirable for good image quality. The method can be incorporated into different acquisitions schemes, including segmented k-space scanning, which allows for contrast variation with the use of magnetization preparation. Head-to-toe images of volunteers were obtained with good quality using 3D spoiled gradient-echo sequences. As an example of magnetization-prepared imaging, fat/water separated images were acquired using chemical shift selective ( For MRI of extended regions of the human body, such as in angiography and cancer screening, the patient table must be moved because the useful field of view (FOV) is limited in clinical scanners. The established method for this purpose is to acquire the MR data at a number of successive stations while the table is at rest (1,2). Alternatively, the MR data are acquired continuously while the table moves, which is technically more demanding but can offer shorter scan time and increased flexibility in the imaging of dynamic processes. Continuously moving table methods can be subdivided into two main approaches: In the first one, data are acquired from transverse (axial) slices positioned at or near the isocenter (3-7). This approach benefits from the good field homogeneity obtainable in transverse slices, but is not optimal from an SNR standpoint, since data are acquired from only a small slice volume. In the second approach, which is addressed in this paper, data are acquired simultaneously from a large 3D volume. Several scanning strategies are possible here, with different tradeoffs among SNR, speed of acquisition, and image quality.Dietrich and Hajnal (8) proposed a continuously moving table method based on 3D Cartesian k-space scanning in which the frequency-encoding (readout) direction is chosen along a transverse direction, the secondary phaseencoding along the direction of motion. To compensate for the table motion, each acquired full set of secondary phase-encoding data is Fourier transformed along the direction of motion and shifted to its corresponding anatomical location in hybrid space (mixed Fourier/spatial domain). A slab-selective RF pulse is applied to avoid signal aliasing along the head-feet direction. Kruger et al. (9) described a method in which the frequency-encoding direction is chosen parallel with the direction of motion, which obviates the need for slab selection. Gradient nonlinearity correction has been incorporated into this scheme (10), allowing larger 3D acquisition volumes. Zhu and D...