2013
DOI: 10.1016/j.molliq.2012.12.028
|View full text |Cite
|
Sign up to set email alerts
|

Extended Hildebrand Solubility Approach applied to piroxicam in ethanol+water mixtures

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
13
0

Year Published

2013
2013
2019
2019

Publication Types

Select...
8

Relationship

1
7

Authors

Journals

citations
Cited by 34 publications
(13 citation statements)
references
References 14 publications
0
13
0
Order By: Relevance
“…In the same way as was previously made, [18,20,21] since we are searching for the best adjust, the first criterion used to define the best polynomial order of W term as function of δ 1 was the fitting standard uncertainties obtained ( Table 4). As another comparison criterion, beside the calculated solubility values, Table 5 also summarises the difference percentages between the experimental solubilities and those calculated by using EHSA.…”
Section: [34] Itmentioning
confidence: 99%
See 2 more Smart Citations
“…In the same way as was previously made, [18,20,21] since we are searching for the best adjust, the first criterion used to define the best polynomial order of W term as function of δ 1 was the fitting standard uncertainties obtained ( Table 4). As another comparison criterion, beside the calculated solubility values, Table 5 also summarises the difference percentages between the experimental solubilities and those calculated by using EHSA.…”
Section: [34] Itmentioning
confidence: 99%
“…These results are similar to those previously described for other drugs. [20][21][22] Moreover, it would just be necessary to find an effective method to calculate the Walker K parameter in order to calculate the W term according to the expression W = 2Kδ 1 δ 2 , because the δ 1 and δ 2 terms would be known, and thus, the drug experimental solubility could be calculated in any mixture. [11] 4.…”
Section: Coefficient or Parametermentioning
confidence: 99%
See 1 more Smart Citation
“…It has also been used in veterinary medicine to treat canines with transitional cell carcinoma of the urinary bladder. 181,182 There have been several publications 64,171,[183][184][185] involving the solubility of piroxicam in organic solvents. Most notably, Bustamante et al 171 measured the mole fraction solubility of piroxicam in 22 different organic solvents, including two saturated hydrocarbons (heptane and cyclohexane), one aromatic hydrocarbon (benzene), one alkyl alkanoate (ethyl ethanoate), one dialkyl ether (1,1′-oxybisethane) and one cyclic ether (1,4-dioxane), two chloroalkanes (trichloromethane and 1,2-dichloroethane) and one chlorinated aromatic hydrocarbon (chlorobenzene), seven alcohols (methanol, ethanol, 1-pentanol, 1-octanol, 1,2-ethanediol, 1,2-propanediol, and 1,2,3-propanetriol), one alkanone (propanone) and one aromatic ketone (acetophenone), and four miscellaneous organic solvents (ethanoic acid, propanoic acid, formamide, and N,Ndimethylformamide) at 298 K and atmospheric pressure.…”
Section: Critical Evaluation Of Experimental Solubility Datamentioning
confidence: 99%
“…It is important to keep in mind that EHSA method has been widely used to study the solubility of a lot of pharmaceutical compounds as has been recently exposed in the literature (Holguín, et al, 2012). Furthermore, it is still employed to evaluate the behavior of drugs in several co-solvent mixtures (Sotomayor, et al, 2013;Gómez, et al, 2013;Rathi, 2011;Dehpande, et al, 2014). On the other hand, it is remarkable that EtOH is one of the more employed co-solvent to develop liquid pharmaceutical dosage forms because of its solubilizing and antimicrobial properties (Smolinske, 1992;Aulton, 2002).…”
Section: Introductionmentioning
confidence: 99%