Extending the Boundaries of Cardiac Resynchronization Therapy: Efficacy in Atrial Fibrillation, New York Heart Association Class II, and Narrow QRS Heart Failure Patients

Wein, Sara; Voskoboinik, Aleksandr; Wein, Lironne; Billah, Baki; Krum, Henry

doi:10.1016/j.cardfail.2009.12.018

Cited by 25 publications

(17 citation statements)

References 26 publications

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“…Сходные наблюдения представ-лены в исследовании PAVE (Left Ventricular-Based Cardiac Stimulation Post AV Nodal Ablation Evaluation) [94]. В нескольких мета-анализах сравнивались результаты CRT среди пациентов с СН тяжелой и средней степени на СР и на ФП [91,92,95]. В целом, в этих исследованиях показано, что у пациентов с ФП изменение ФВ было сходным или даже лучше, но снижение ФК СН по NYHA, ТШХ или качество с имплантацией СРТ, или через несколько недель, когда гарантировано адекватное функционирование электродов и устройства.…”

Section: пациенты с сердечной недостаточностью широким комплексом Qrunclassified

2013 Esc Guidelines on Cardiac Pacing and Cardiac Resynchronization Therapy

Brignole¹,

Auricchio²,

et al. 2014

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Section: пациенты с сердечной недостаточностью широким комплексом Qrunclassified

2013 Esc Guidelines on Cardiac Pacing and Cardiac Resynchronization Therapy

Brignole¹,

Auricchio²,

et al. 2014

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“…In contrast to our results, some previous studies in AF patients demonstrated that, despite similar changes in LVEF, there was less improvement in NYHA functional class. 25,26,31 An important issue is the CRT response rate, bearing in mind that definitions of CRT response in the literature differ widely. 32 It is interesting to observe that neither SR nor permanent AF significantly influenced the percentage of responders in this sample, either clinical (SR 78.6% vs. AF 80.7%) or echocardiographic (SR 77.4% vs. AF 82.1%).…”

Section: Discussionmentioning

confidence: 99%

Does permanent atrial fibrillation modify response to cardiac resynchronization therapy in heart failure patients?

Abreu

Oliveira

Cunha

et al. 2017

Revista Portuguesa de Cardiologia

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Introduction:The benefits of cardiac resynchronization therapy (CRT) documented in heart failure (HF) may be influenced by atrial fibrillation (AF). We aimed to compare CRT response in patients in AF and in sinus rhythm (SR). Methods: We prospectively studied 101 HF patients treated by CRT. Rates of clinical, echocardiographic and functional response, baseline NYHA class and variation, left ventricular ejection fraction, volumes and mass, atrial volumes, cardiopulmonary exercise test (CPET) duration (CPET dur), peak oxygen consumption (VO 2 max) and ventilatory efficiency (VE/VCO 2 slope) were compared between AF and SR patients, before and at three and six months after implantation of a CRT device. Results: All patients achieved ≥95% biventricular pacing, and 5.7% underwent atrioventricular junction ablation. Patients were divided into AF (n=35) and SR (n=66) groups; AF patients were older, with larger atrial volumes and lower CPET dur and VO 2 max before CRT. The percentages of clinical and echocardiographic responders were similar in the two groups, but there were more functional responders in the AF group (71% vs. 39% in SR patients; p=0.012). In SR patients, left atrial volume and left ventricular mass were significantly reduced (p=0.015 and p=0.021, respectively), whereas in AF patients, CPET dur (p=0.003) and VO 2 max (p=0.001; 0.083 ageadjusted) showed larger increases. * Corresponding author. E-mail address: ananabreu@hotmail.com (A. Abreu).http://dx.doi.org/10.1016/j.repc.2017.02.016 0870-2551/© 2017 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. All rights reserved. Document downloaded from http://www.elsevier.es, day 06/03/2018. This copy is for personal use. Any transmission of this document by any media or format is strictly prohibited. Document downloaded from http://www.elsevier.es, day 06/03/2018. This copy is for personal use. Any transmission of this document by any media or format is strictly prohibited. 688A. Abreu et al. Conclusion:Clinical and echocardiographic response rates were similar in SR and AF patients, with a better PALAVRAS-CHAVE

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“…Las mismas conclusiones se observaron en el estudio PAVE 94 . Para contrarrestar la ausencia de ensayos clínicos aleatorizados, algunos metanálisis han comparado los resultados de la TRC en pacientes con IC moderada o grave y SR con los de aquellos que tienen FA 91,92,95 . En general, estos estudios constataron que, en pacientes con FA, el cambio de la FEVI fue similar (o aun mejor), pero la mejoría de la clase NYHA, la prueba de los 6 min de marcha o la calidad de vida fueron considerablemente más bajas.…”

Section: Insuficiencia Cardiaca Qrs Intrínseco ≥ 120 Ms Y Fracción Dunclassified