Abstract:The limits of previous methods promote us to design a new approach (named PRESTAGE) to predict proton single event effect (SEE) cross-sections using heavy-ion test data. To more realistically simulate the SEE mechanisms, we adopt Geant4 and the location-dependent strategy to describe the physics processes and the sensitivity of the device.Cross-sections predicted by PRESTAGE for over twenty devices are compared with the measured data. Evidences show that PRESTAGE can calculate not only single event upsets induced by proton indirect ionization, but also direct ionization effects and single event latch-ups. Most of the PRESTAGE calculated results agree with the experimental data within a factor of 2-3.