Extensive Involvement of the Myocardium and the Cardiac Conduction System in a Case of Wegener's Granulomatosis.

Ohkawa, Shin-ichiro; Miyao, Mariko; Chida, Kouji; Mizuuchi, Tomoko; Kida, Kouzui; Takubo, Kaiyo; Ohtsubo, Kohichiro

doi:10.1536/jhj.40.509

Cited by 14 publications

(12 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Forstot et al [7]reported conduction system granulomata in 17% of WG patients, and arteritis of the blood supply to the atrioventricular node in 11% of cases. Several cases of high-grade atrioventricular block, including complete heart block, have been reported in the literature [4, 7, 11, 40, 41, 42, 43, 44]. Notably, the block may be reversible and responsive to intensification of the pharmacological therapy for WG.…”

Section: Conduction Disorders and Arrhythmiasmentioning

confidence: 99%

See 1 more Smart Citation

The Heart in Wegener’s Granulomatosis

2004

View full text Add to dashboard Cite

Wegener’s granulomatosis (WG) is a necrotizing vasculitis that mainly affects the respiratory tract and kidneys. Of note, involvement of the heart is being increasingly recognized in these patients. Cardiac manifestations can arise from the coronary arteries, pericardium, myocardium, endocardium, valves, conduction system and great vessels, but in most cases cardiac involvement is clinically silent. Consequently, a regular cardiovascular evaluation, including echocardiography, should be performed in every patient with WG, while patients with WG flare should be closely monitored for cardiac complications even in the absence of specific symptoms.

show abstract

Section: Conduction Disorders and Arrhythmiasmentioning

confidence: 99%

“…Although the incidence of arrhythmias in WG patients has not been investigated, it seems that atrial and supraventricular arrhythmias are much more common than ventricular arrhythmias [2, 6, 8, 11, 42]. Patients may present with palpitations, light-headedness or even syncope.…”

Section: Conduction Disorders and Arrhythmiasmentioning

confidence: 99%

The Heart in Wegener’s Granulomatosis

2004

View full text Add to dashboard Cite

show abstract

“…Since then, there have only been 13 cases previously reported in the published literature and all but one case was associated with systemic disease (Table 1) [1,[3][4][5][6][7][8][9][10][11][12][13][14]. Complete AV block was present at disease onset in 50% and in 70% by one year.…”

Section: Discussionmentioning

confidence: 99%

A patient with Wegener's granulomatosis in apparent remission presenting with complete atrioventricular block

Cassidy

Sowden

Brockbank

et al. 2011

Journal of Cardiology Cases

View full text Add to dashboard Cite

Wegener's granulomatosis is a systemic necrotizing granulomatous vasculitis of small-to medium-sized vessels typically affecting upper and lower airways, lungs, and kidneys. Cardiac involvement is less common and conducting tissue involvement is extremely rare. Cardiac manifestations are often not clinically apparent, but are associated with increased mortality. We report the case of a 36-year-old female with Wegener's thought to be in remission, presenting in complete atrioventricular (AV) block, with echocardiographic evidence of basal interatrial septum and basal lateral left atrial wall thickening. Despite immunosuppression therapy a permanent pacemaker was required for recurring complete AV block. Although rare, this case emphasizes the need for careful and regular screening for cardiac involvement in this multi-system condition.

show abstract

“…In the literature, we identified only nine studies mentioning Wegener's granulomatosis and FUO together (5)(6)(7)(8)(9)(10)(11)(12)(13). In the study of Sipahi et al (3), this disease was identified in only 3 cases out of a total of 857.…”

Section: Discussionmentioning

confidence: 99%

A Case with Fever of Unknown Origin Diagnosed as Wegener Granulomatosis

et al. 2010

View full text Add to dashboard Cite

Abst ractFever of unknown origin (FUO) was described in 1961 by Petersdorf and Beeson as a fever above 38.3°C that lasts more than three weeks and cannot be diagnosed despite a one-week hospitalized examination. In 1991, Durack and Street made a different FUO description for patients with nosocomial infections, human immunodeficiency virus (HIV) and neutropenia. Along with this reconsideration, the investigation period was limited to one week of investigation, three days of hospitalization or three clinical visits. In the literature, the most frequent cause of FUO is infections followed by neoplasms and connective vascular diseases, respectively. The etiology in 5-15% of patients can not be diagnosed despite detailed examination. Here, we present a 75-year-old patient admitted to the hospital with a two-week history of fever, fatigue and lack of appetite. He had been examined in the infection and lung diseases clinics over a three-month period without diagnosis. In our internal medicine clinic, we diagnosed the patient as Wegener granulomatosis and a satisfactory response to the therapy was observed. (Turk J Rheumatol 2010; 25: 159-61

show abstract

Extensive Involvement of the Myocardium and the Cardiac Conduction System in a Case of Wegener's Granulomatosis.

Cited by 14 publications

References 6 publications

The Heart in Wegener’s Granulomatosis

The Heart in Wegener’s Granulomatosis

A patient with Wegener's granulomatosis in apparent remission presenting with complete atrioventricular block

A Case with Fever of Unknown Origin Diagnosed as Wegener Granulomatosis

Contact Info

Product

Resources

About