“…There are histological variations (clear cell, epithelioid, granular cell, and myxoid changes) and secondary degenerative changes (hyaline degeneration, cystic change, myxoid degeneration, infection, necrosis, and calcification) in leiomyoma of the oral cavity and head and neck region. It is thought that these changes result from deficient blood supply, leading to a replacement of muscle fibers by collagen, hyaline material, calcium, mucopolysaccharide, or a combination of these factors (13,14).…”