2014
DOI: 10.1016/j.radonc.2014.07.013
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External beam radiotherapy plus single-fraction high dose rate brachytherapy in the treatment of locally advanced prostate cancer

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Cited by 21 publications
(14 citation statements)
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References 46 publications
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“…Recent advances such as intensity-modulated radiation therapy, fractionated delivery regimens and volumetric modulated arc therapy (2-3) aim to reduce toxicity. However, both late and acute symptoms and side effects can still occur and impact on quality of life (QOL) (4,5).…”
Section: Introductionmentioning
confidence: 99%
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“…Recent advances such as intensity-modulated radiation therapy, fractionated delivery regimens and volumetric modulated arc therapy (2-3) aim to reduce toxicity. However, both late and acute symptoms and side effects can still occur and impact on quality of life (QOL) (4,5).…”
Section: Introductionmentioning
confidence: 99%
“…Recent advances such as intensity-modulated radiation therapy, fractionated delivery regimens and volumetric modulated arc therapy 2 , 3 aim to reduce toxicity. However, both late and acute symptoms and side effects can still occur and impact on quality of life (QOL) 4 5 Therefore, robust plans to ensure patients’ supportive needs are met both during treatment and beyond need to be implemented 6 …”
Section: Introductionmentioning
confidence: 99%
“…3 Dose escalation can be achieved with precise radiotherapy techniques such as 3D-CRT or intensity-modulated radiotherapy (IMRT), or by adding a boost delivered with high-dose rate brachytherapy (HDRB) or IMRT. [4][5][6][7] Overall survival in high risk patients can be further improved by combining EBRT with androgen deprivation therapy (ADT). 8,9 …”
Section: Introductionmentioning
confidence: 99%
“…SBRT allows radiation oncologists to deliver a higher dose in far fewer fractions compared with conventional radiation therapy. The prescription of high doses in a single fraction is being used more widely . However, radiation‐induced damage to normal tissues, for instance, peripheral nerves, has been a concern in clinical practice.…”
mentioning
confidence: 99%
“…The prescription of high doses in a single fraction is being used more widely. [2][3][4] However, radiation-induced damage to normal tissues, for instance, peripheral nerves, has been a concern in clinical practice.…”
mentioning
confidence: 99%