Postthrombotic syndrome
(PTS) is a late outcome of deep vein thrombosis characterized by
cramping pain, swelling, hyperpigmentation, eczema,
lipodermatosclerosis, and ulceration in the leg due to increased
venous outflow resistance and reflux venous flow. Newer surgical
and endovascular interventions have a promising result in the
management of postthrombotic syndrome. Early surgical or
endovascular interventions in appropriately selected patients may
decrease the incidence of recurrent ulceration and skin changes and
provide a better quality of life. Duplex and IVUS (intravenous
ultrasound) along with venography serve as cornerstone
investigative tools for assessment of reflux and obstruction.
Venous obstruction, if present, should be addressed earlier than
reflux. It requires endovenous stenting, endophlebectomy, or open
bypass procedures. Venous stripping, foam sclerotherapy,
radiofrequency, or laser ablation are used to abolish superficial
venous reflux. Valvuloplasty procedures are useful for incompetent
but intact deep venous valves, while transposition or axillary
vein autotransplantation is done for completely destroyed
valves.