External validation of the PALIAR index for patients with advanced, nononcologic chronic diseases

Gómez-Aguirre, Noelia; Fuertes-Ruiz, Daniel; Gracia-Tello, Borja; Clemente-Sarasa, Carolina; Artajona-Rodrigo, Ester; Cabrerizo-García, José-Luis; Escalante-Yangüela, Begoña De; Bueno-Castel, María-Carmen; Velilla-Marco, José; Díez-Manglano, Jesús

doi:10.1007/s40520-018-0980-3

Cited by 9 publications

(9 citation statements)

References 23 publications

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“…We did not find differences by gender in terms of in-patient mortality or survival during the follow-up. This is in line with two Spanish studies performed in a population with similar characteristics to ours, although some previous reports have shown higher post-hospital mortality in males [10,23,24,25].…”

Section: Discussionsupporting

confidence: 93%

“…The figure for 1-year mortality observed in our study (46%) is in accordance with results published in other similar Spanish cohorts, where they ranged between 40% and 50%. In these studies as well, no differences were found in mortality by gender [23,24,38,39,40]. Additionally, our study confirms the reliability of the PROFUND and Charlson indexes in the prediction of 1-year mortality.…”

Section: Discussionsupporting

confidence: 85%

“…However, the mean age of our population was nine years older, and the Charlson comorbidity index almost three times higher [27]. Our data on hospital mortality are similar to what was observed in studies performed with similar inclusion criteria, and we believe that the differences in mortality rates may simply reflect a sicker patient population [23,24,25]. Previous studies have shown that 70-80% of patients that die in hospital are frail, older patients with multiple comorbidities who were admitted through emergency rooms [28].…”

Section: Discussionsupporting

confidence: 78%

“…However, the number of included patients was considerable, and their characteristics very similar to those observed in multicenter studies performed in the same geographical area. [17,23,24,38,39,40] Second, our study focuses on hospitalized elderly multimorbidity patients requiring complex health care, and their definition is not universally accepted. Currently, multimorbidity is defined as the presence of two or more chronic diseases in the same subject or the combination of one chronic illness with at least one other disease (acute or chronic) or bio-psychosocial factor [41].…”

Section: Discussionmentioning

confidence: 99%

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Multimorbidity gender patterns in hospitalized elderly patients

et al. 2020

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Patients with multimorbidity and complex health care needs are usually vulnerable elders with several concomitant advanced chronic diseases. Our research aim was to evaluate differences in patterns of multimorbidity by gender in this population and their possible prognostic implications, measured as in-hospital mortality, 1-month readmissions, and 1-year mortality. We focused on a cohort of elderly patients with well-established multimorbidity criteria admitted to a specific unit for chronic complex-care patients. Multimorbidity criteria, the Charlson, PROFUND and Barthel indexes, and the Pfeiffer test were collected prospectively during their stays. A total of 843 patients (49.2% men) were included, with a median age of 84 [interquartile range (IQR) 79-89] years. The women were older, with greater functional dependence [Barthel index: 40 (IQR:10-65) vs. 60 (IQR: 25-90)], showed more cognitive deterioration [Pfeiffer test: 5 (IQR:1-9) vs. 1 (0-6)], and had worse scores on the PROFUND index [15 (IQR:9-18) vs. 11.5 (IQR: 6-15)], all p <0.0001, while men had greater comorbidity measured with the Charlson index [5 (IQR: 3-7) vs. 4 (IQR: 3-6); p = 0.002]. In the multimorbidity criteria scale, heart failure, autoimmune diseases, dementia, and osteoarticular diseases were more frequent in women, while ischemic heart disease, chronic respiratory diseases, and neoplasms predominated in men. In the analysis of grouped patterns, neurological and osteoarticular diseases were more frequent in females, while respiratory and cancer predominated in males. We did not find gender differences for in-hospital mortality, 1-month readmissions, or 1-year mortality. In the multivariate analysis age, the Charlson, Barthel and PROFUND indexes, along with previous admissions, were independent predictors of 1-year mortality, while gender was non-significant. The Charlson and PROFUND indexes predicted mortality during follow-up more accurately in men than in women (AUC 0.70 vs. 0.57 and 0.74 vs. 0.62, respectively), with both p<0.001. In conclusion, our study shows differing patterns of multimorbidity by gender, with greater functional impairment in women and more comorbidity in men, although without differences in the prognosis. Moreover, some of these prognostic indicators had differing accuracy for the genders in predicting mortality.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 85%

Section: Discussionsupporting

confidence: 78%

Section: Discussionmentioning

confidence: 99%

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Multimorbidity gender patterns in hospitalized elderly patients

et al. 2020

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“…El índice de comorbilidad de Charlson 16,17 , sólo evalúa patologías, por lo que no debería interpretarse de forma aislada, teniendo en cuenta que en anciano hay que realizar una valoración integral en que se tengan en cuenta otros aspectos, como son los funcionales, psicosociales y mentales 7,14,102,[118][119][120][121]…”

Section: Comorbilidad E íNdice De Charlsonunclassified

Índice de FRAX® como índice de comorbilidad y/o mortalidad en población anciana

Silva¹

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Regresión logística para mortalidad a 6 meses para Índice de FRAX® para fractura de cadera: 123 4.3.2. Regresión logística para mortalidad a 6 meses para Índice de FRAX® para fractura mayor osteoporótica: 127 4.3.3. Regresión logística para Índice de FRAX® para fractura de cadera y mortalidad a 1 año: ...... 4.3.4. Regresión logística para Índice de FRAX® para fractura mayor osteoporótica y mortalidad a 1 año: 135 4.3.5. Regresión logística para índice de FRAX® para fractura mayor osteoporótica e ingresos a 1 año: 139 4.3.6. Regresión logística para índice de FRAX® para fractura de cadera e ingresos a

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