Extra-articular en bloc resection of the talocrural and the talocalcaneonavicular joints for primary malignant synovial tumour (myxoinflammatory fibroblastic sarcoma)

Abstract

A 13-year-old boy presented with a diagnosis of intra-articular myxoinflammatory fibroblastic sarcoma of the ankle. There had been no previous description of a sarcoma arising directly from the synovium of the ankle and limb salvage for malignant tumours of the ankle has rarely been reported. We treated him by peritalar extra-articular resection, and draw attention to this rare tumour and to a technique of limb-sparing resection of the ankle joint.

Primary intra‐articular sarcoma: a clinicopathological study of 15 cases

“…Myxoinflammatory fibroblastic sarcoma is a relatively recently described tumour that is thought to be biologically low‐grade . Although their growth may be associated closely with the synovium of tendon sheaths, only one report described a tumour arising within the ankle joint of a 13‐year‐old male . The patient received a limb‐sparing resection and has no evidence of disease after 26 months.…”

“…36,37 Although their growth may be associated closely with the synovium of tendon sheaths, only one report described a tumour arising within the ankle joint of a 13-year-old male. 33 The patient received a limb-sparing resection and has no evidence of disease after 26 months. The one patient in our series is currently free of disease 75 months after amputation.…”

“…Sarcomas infrequently affect joints; however, when articulations are involved it is due usually to the contiguous spread of tumour from neighbouring soft tissue or osseous structures. Primary sarcomas of the joint are extremely rare . The few cases that have been published reveal that most arise in the knee joint of adults, and the most common types are synovial sarcoma and extraskeletal myxoid chondrosarcoma.…”

Myxoinflammatory Fibroblastic Sarcoma: Report of a Case and Review of the Literature

“…Myxoinflammatory fibroblastic sarcomas are rare, lowgrade tumors with myofibroblastic differentiation and typically occur in adults [7]. Although myofibroblastic lesions account for about 12% of pediatric soft-tissue tumors in children, fewer than 10 MIFS have thus far been reported in childhood (Table 2) [1,[8][9][10][11].…”

Myxoinflammatory Fibroblastic Sarcoma in Children and Adolescents: Clinicopathologic Aspects of a Rare Neoplasm

“…Although the clinicopathologic features, immunohistochemistry, and genetic aberrations of MIFS in adults are well described [3,4,6,[8][9][10][11][12][13][14][15], only a few cases have been reported in children and adolescents [3,6,7,[16][17][18]. Here we report the clinicopathologic, immunohistochemical, and molecular cytogenetic findings in 5 examples of MIFS in children and adolescents, 1 of which was previously published [7].…”