This paper presents the novel topology of Photo Voltaic (PV) power generation system with simple Maximum Power Point Tracking (MPPT) algorithm in voltage operating mode. Power circuit consists of high output voltage DC-DC boost converter which maximizes the output of PV panel. Usually traditional DC-DC boost converters are used for such application, but they are not the most suitable solution due to output limitation, lower efficiency and require more sensors with complex control algorithm. Further on, the effects of parasitic elements are suppressed, as well as the power transfer efficiency of DC-DC converters for PV integration. Hence, to overcome these difficulties this paper investigates a DC-DC boost converter together with the additional parasitic component within the circuit to provide high output voltages for maximizing the PV power generation. The proposed power system circuit substantially improves the high output-voltage by a simple MPPT closed loop proportional-integral (P-I) controller, and requires only two sensor for feedback needs. The complete numerical model of the converter circuit along with PV MPPT algorithm is developed in numerical simulation (Matlab/Simulink) software. A detailed performance analysis is carried out under both PV panel irradiation (high/low) and load regulation conditions. Numerical results obtained in this paper are in the agreement with the theoretical developments, proving the effectiveness of the proposed topology. Index Terms-DC-DC boost converter, Pulse width modulation (PWM), Power transfer efficiency, Photo voltaic power generation, PI controller, Maximum power point tracking (MPPT), High voltage application.