Extra-Intestinal Manifestations of Crohn Disease and Chronic Ulcerative Colitis in the Oral Cavity

Abstract

Subject. The review allows us to consider the issues of etiopathogenesis, the prevalence of Crohn disease and ulcerative colitis, as well as their manifestations on the oral mucosa.
 The aim is to conduct a systematic analysis of modern indigenous and foreign literary sources to determine some features of etiopathogenesis, prevalence and manifestations in the oral cavity of Crohn disease and chronic non-specific ulcerative colitis.
 Methodology. The search for research works on the etiology and pathogenesis of Crohn disease, ulcerative colitis was carried out using the following databases: PubMed, Web of Science, elibrary.ru , Scopus in the period from 2010 to 2021, as well as the review includes some significant publications concerning the manifestations in the oral cavity of CD and NCUC for the period from 2014 to 2021. The following keywords were used: chronic ulcerative colitis, Crohn disease, caries, periodontal disease, oral mucosa, aphthae, dysbiosis.
 Results. Among the main dental diseases, pathology of hard tissues, inflammatory diseases of periodontal tissues, pathology of the oral mucosa against the background of pronounced dysbiosis most often prevails. During a comprehensive examination of these patients, it is very important to analyze not only the features of the manifestations of Crohn disease and ulcerative colitis, but also to evaluate their manifestations on the hard tissues of the teeth, the oral mucosa and periodontal tissues.
 Conclusions. Thus, the analysis of the literature data obtained is of particular relevance for identifying some features of the state of dental status in CD and NCUC in the Republic of Bashkortostan and the basis for the development of algorithms for diagnostic features of the management of this category of persons.