Extra-Nasopharyngeal Angiofibroma in a Pre-Pubertal Child

Ganguly, Subhro; Gawarle, Surendra H.; Keche, Prashant

doi:10.7860/jcdr/2017/27897.10771

Cited by 3 publications

(6 citation statements)

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“…Celik B et al proposed reserving the term "Atypical Angio broma" for such neoplasms. 4 Clinically, ENA is characterized as a large, benign, highly vascular, and locally aggressive tumor, with an average size of 5.9 cm in one study. This tumor is predominantly found in males in their third decade.…”

Section: Discussionmentioning

confidence: 97%

“…This tumor is predominantly found in males in their third decade. 3,4 The symptoms of ENA can vary depending on their location. In intra-oral presentations, they may appear sessile or pedunculated, reddish pink, or similar to the surrounding mucosa.…”

Section: Discussionmentioning

confidence: 99%

“…ENAs have been recorded in various areas, including the maxillary sinus, paranasal sinuses, nasal cavity, buccal and infratemporal space, mandible, and lips. [3][4][5][6] Despite their rarity, comprising less than 0.05% of all head and neck tumors, ENAs are of great clinical interest due to their propensity to cause profuse bleeding. The etiology of these tumors is linked to the expression of male sex hormones (androgens and progesterone), genetic factors, molecular alterations, or human papillomavirus infection.…”

Section: Discussionmentioning

confidence: 99%

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2024

IJDE

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Angiofibromas, accounting for a mere 0.05-0.5% of all head and neck neoplasms, are uncommon benign tumors originating from connective tissue and characterized by a high vascularity and local aggressiveness. Juvenile Nasopharyngeal Angiofibroma, extensively discussed in medical literature, represents the most common subtype and is typically found in the nasopharynx. Extra-nasopharyngeal angiofibromas, which occur in locations outside the nasopharynx, are quite rare, with the maxillary sinus being the most typical site according to existing research. This paper presents a unique case of Extra-nasopharyngeal Angiofibroma affecting the hard palate in an adult female. This case is noteworthy due to the tumor's anterior hard palate location, its occurrence in a female patient, and its clinical resemblance to a fibroma, making it the first reported case of its kind.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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2024

IJDE

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“…Their findings included only 22 patients aged under 12 years, only one of them was epiglottic ( 2 , 3 ). To our knowledge, only seven cases in children younger than 12 years have been published since Windfuhr and Vent’s ( 1 ) review: two nasal septum ENA reports by Singh et al ( 4 ) and Ganguly et al ( 5 ), an oropharyngeal case by Gupta et al ( 6 ), two inferior turbinate cases by Kim and Choi ( 7 ), an ethmoid case by Uwents et al ( 8 ), and an inferior turbinate and lateral wall of nasopharynx case by Yan et al ( 9 ).…”

Section: Discussionmentioning

confidence: 99%

Recurrent Pediatric Extranasopharyngeal Angiofibroma of the Epiglottis: Case Report

Hernando,

Lowy,

Agra

et al. 2023

TAO

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Angiofibroma is a non-encapsulated, highly vascular tumor that usually originates in the nasopharynx. Laryngeal cases of extranasopharyngeal angiofibroma (ENA) are a very rare pathology, especially in children. Only eight ENA laryngeal cases have been described in the literature, and only one of them is a pediatric case. In this report we present an 11-year-old child with epiglottic ENA resected with transoral endoscopic ultrasonic surgery (TOUSS) with review of the literature. Because of reccurrence after five months he underwent re-excision with CO 2 laser. Recurrences in ENA are infrequent, but as demonstrated in our case, close endoscopic follow-up is mandatory in this location. Endoscopic hemostatic procedures like TOUSS and CO 2 laser ensure bloodless surgery for the management of this type of vascular laryngeal tumors.

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“…The main treatment for extranasopharyngeal angiofibroma is surgical resection, which is usually performed via the transnasal endoscopic, lateral rhinotomy incision, or transoral approaches, depending on the site and size of the tumor. We reviewed the surgical procedures performed for extrapharyngeal angiofibromas in children over the last 30 years, and found that tumors in the septum, inferior turbinate, and middle turbinate were mostly commonly removed using nasal endoscopic resection ( e.g., Ganguly et al [ 16 ] and Singh et al [ 17 ]). Gaffney et al [ 18 ] and Huang et al [ 8 ] performed lateral rhinotomy to remove tumors originating from the inferior and middle turbinates, respectively.…”

Section: Discussionmentioning

confidence: 99%

Extranasopharyngeal angiofibroma in children: A case report

Yan¹,

Lai²,

Wu³

et al. 2022

WJCC

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BACKGROUND Sporadic cases of extranasopharyngeal angiofibroma in children, especially preschool children, have been reported in the literature. CASE SUMMARY We present a case of extranasopharyngeal angiofibroma in a 4-year-old boy. The presenting symptoms, imaging findings, treatment, histological appearance, and follow-up data are described in detail. For this patient, we performed embolization on two occasions, and then, resected the tumor completely. During the treatment, the patient developed a soft-palate perforation due to aseptic necrosis. However, the healing ability was good, and the perforation healed spontaneously. We additionally reviewed all pediatric cases of extranasopharyngeal angiofibroma published up to 30 June 2020 in the PubMed, Baidu Scholar, Scopus, and Web of Science databases. We identified 45 pediatric patients [average (10.98 ± 4.86), boys 39 (86.7%)]. The highest proportion of cases occurred in adolescence [22 (48.9%)]. The top three sites of occurrence of extranasopharyngeal angiofibroma in children were the maxillary sinus, nasal septum, and inferior turbinate. CONCLUSION Extranasopharyngeal angiofibromas can occur throughout childhood, and predominantly present with nasal obstruction and spontaneous rhinorrhagia.

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Extra-Nasopharyngeal Angiofibroma in a Pre-Pubertal Child

Cited by 3 publications

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Recurrent Pediatric Extranasopharyngeal Angiofibroma of the Epiglottis: Case Report

Extranasopharyngeal angiofibroma in children: A case report

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