Cell Biochem. Funct.
 2000
DOI: 10.1002/(sici)1099-0844(200001/03)18:1<67::aid-cbf852>3.0.co;2-n
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Extracellular Ca2+ suppresses endotoxin-inducible tissue factor activation in monocytic THP-1 cells

Arthur J. Chu
1
,
Melissa J. Fox
2
,
J.K. Prasad
3

Abstract: Our results demonstrate that [Ca(2+)](ex) blocked LPS recognition without affecting its receptor expression on THP-1 monocytes. This insensitivity to LPS thereby resulted in the depressed inducible monocytic TF expression and activation.

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