Extracellular DNA controls expression ofPseudomonas aeruginosagenes involved in nutrient utilization, metal homeostasis, acid pH tolerance, and virulence
Abstract:ABSTRACTPseudomonas aeruginosa grows in extracellular DNA-enriched biofilms and infection sites. Extracellular DNA (eDNA) is generally considered a structural biofilm polymer required for aggregation and biofilm maturation. In addition, eDNA can sequester divalent metal cations, acidify the growth media, and serve as a nutrient source. Here we determine the transcriptome of planktonic P. aeruginosa grown in the presence of e… Show more
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