2021
DOI: 10.20944/preprints202108.0439.v1
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Extracellular Matrix Components as Diagnostic Tools in Inflammatory Bowel Disease

Abstract: Work from the last years indicate that the extracellular matrix (ECM) plays a direct role in vari-ous cellular processes including proliferation, migration and differentiation. Besides homeostat-ic processes, its regulatory function in inflammation becomes more and more evident. In in-flammation like inflammatory bowel disease, the ECM composition is constantly remodeled which can result in a structuring of fistulizing disease course. Thus, tracking early ECM changes might bear the potential to predict the dis… Show more

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