2024
DOI: 10.1038/s41419-024-07003-y
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Extracellular vesicle-associated DNA: ten years since its discovery in human blood

Thupten Tsering,
Amélie Nadeau,
Tad Wu
et al.

Abstract: Extracellular vesicles (EVs) have emerged as key players in intercellular communication, facilitating the transfer of crucial cargo between cells. Liquid biopsy, particularly through the isolation of EVs, has unveiled a rich source of potential biomarkers for health and disease, encompassing proteins and nucleic acids. A milestone in this exploration occurred a decade ago with the identification of extracellular vesicle-associated DNA (EV-DNA) in the bloodstream of a patient diagnosed with pancreatic cancer. S… Show more

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Cited by 2 publications
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