2024
DOI: 10.3390/biom14030277
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Extracellular Vesicles as Delivery Vehicles for Non-Coding RNAs: Potential Biomarkers for Chronic Liver Diseases

Arianna Ferro,
Gabriele Saccu,
Simone Mattivi
et al.

Abstract: In recent years, EVs have emerged as promising vehicles for coding and non-coding RNAs (ncRNAs), which have demonstrated remarkable potential as biomarkers for various diseases, including chronic liver diseases (CLDs). EVs are small, membrane-bound particles released by cells, carrying an arsenal of ncRNAs, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and other ncRNA species, such as piRNAs, circRNAs, and tsRNAs. These ncRNAs act as key regulators of gene expression, splicing, and translation,… Show more

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Cited by 8 publications
(1 citation statement)
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“…One essential requisite to be defined as biomarker is the non-invasiveness of the material sampling procedure. Thus, we further our research into potential RBP transcripts as biomarkers for PSC and CCA, by performing a bioinformatics analysis to investigate whether RBPs could be found differentially present in liver tissue and body fluids (as well as in extracellular vesicles (EVs), which are considered as one of the optimal sources of biomarkers due to their biogenesis and the molecular information they carry from the source organs) ( Ferro et al, 2024 ).…”
Section: Introductionmentioning
confidence: 99%
“…One essential requisite to be defined as biomarker is the non-invasiveness of the material sampling procedure. Thus, we further our research into potential RBP transcripts as biomarkers for PSC and CCA, by performing a bioinformatics analysis to investigate whether RBPs could be found differentially present in liver tissue and body fluids (as well as in extracellular vesicles (EVs), which are considered as one of the optimal sources of biomarkers due to their biogenesis and the molecular information they carry from the source organs) ( Ferro et al, 2024 ).…”
Section: Introductionmentioning
confidence: 99%