Antiphospholipid Syndrome - Recent Advances in Clinical and Basic Aspects 2022
DOI: 10.5772/intechopen.97412
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Extracellular Vesicles: Intercellular Communication Mediators in Antiphospholipid Syndrome

Abstract: Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by thrombosis, obstetric complications and the presence of antiphospholipid antibodies (aPL) that cause endothelial injury and thrombophilia. Extracellular vesicles are involved in endothelial and thrombotic pathologies and may therefore have an influence on the prothrombotic status of APS patients. Intercellular communication and connectivity are important mechanisms of interaction between healthy and pathologically altered cells. … Show more

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