Extracorporeal Circulation as an Alternative to Open-Chest Cardiac Compression for Cardiac Resuscitation

Gazmuri, Raúl J.; Weil, Max Harry; Terwilliger, Karl; Shah, Dinesh; Duggal, Chandresh; Tang, Wanchun

doi:10.1378/chest.102.6.1846

Cited by 16 publications

(4 citation statements)

References 30 publications

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“…First, we were unable to stratify the types of CPR interventions due to the heterogeneity of CPR interventions (including defibrillation, anti-arrhythmic drugs, adrenergic drugs, and mechanical CPR). Efforts were made to provide specific information in each article in Supplementary Material B [40–256] to identify the type of VF induction used in the experiment of interest. Second, the quality of the included studies was not assessed.…”

Section: Discussionmentioning

confidence: 99%

Systematic review of swine models for ventricular fibrillation induction in evaluating cardiopulmonary resuscitation methods

Low,

Azahar,

Samson

et al. 2024

Cardiology Plus

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Background and purpose: Ventricular fibrillation (VF) has been studied using a variety of swine models, historically balloon occlusion of the coronary artery and asphyxiation, and more recently, percutaneous electrical induction. These methods differ in face and construct validity, as well as requirement for expertise, cost, and duration. This study aimed to provide a systematic review these methods and their selection in research. Methods: Electronic searches were conducted in PubMed, Scopus, and Google Scholar. The Utstein-Style Guidelines for Uniform Reporting of Laboratory cardiopulmonary resuscitation (CPR) research were used to identify the extracted variables by two independent investigators. Discrepancy was resolved by discussion with the third investigator. Results: We included 236 studies published from 1990 to 2024. The most commonly used method was electrical induction using a pacing wire cannulated through the external jugular vein into the right ventricle (n = 112), followed by transthoracic electrical induction (n = 28), asphyxiation (n = 20), electrical induction via two subcutaneous needles (n = 15), and balloon occlusion (n = 10). The mean and standard deviation (SD) of the untreated VF duration were 6.9 and 5.0 minutes, respectively. Female and male pigs were used exclusively in 52 and 45 studies, respectively; both sexes were used in 31 studies; 106 studies not reporting the sex. The mean weight of the pigs was 30.2 ± 12.4 kg in 209 studies, and the number of pigs used in the studies ranged from 2 to 271 with a median of 20 (interquartile range: 15–30) pigs in 223 studies. The four most commonly used drugs for anesthesia/preparation were ketamine (n = 145), propofol (n = 76), isoflurane (n = 68), and pentobarbital (n = 61), either alone or in combination. Higher current and voltage were used for less invasive methods. Conclusions: The two most common electric method to induce VF were invasive pacing at the right ventricle and non-invasive transthoracic electrical induction. Asphyxiation was the most common ischemic VF induction. The choice of the VF induction method depends on cost, expertise, feasibility, and the nature of the CPR intervention to be tested.

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Section: Discussionmentioning

confidence: 99%

Systematic review of swine models for ventricular fibrillation induction in evaluating cardiopulmonary resuscitation methods

Low,

Azahar,

Samson

et al. 2024

Cardiology Plus

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“…The components of technical devices themselves also vary considerable as well. In order to understand the essence of the ECLS therapy, it is necessary to consider the configuration of partial (or in some cases full) blood bypass using an artificial pump and the integrated blood oxygenator [7,8].…”

Section: Types Of Pumps For Extracorporeal Perfusionmentioning

confidence: 99%

Practical and Theoretical Considerations for ECMO System Development

Khodeli¹,

Chkhaidze²,

Partsakhashvili³

et al. 2016

Extracorporeal Membrane Oxygenation: Advances in Therapy

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Extracorporeal membrane oxygenation (ECMO) is a well-established therapy for the temporary substitution for the heart and/or lungs in patients with acute cardiac or pulmonary failure. Recently, the development of portable systems has allowed for implementation of therapy outside of the intensive care units. ECMO can even be initiated in out-of-hospital situations to allow for patient stabilization and subsequent transfer to an appropriate hospital. This chapter will focus on the authors' development of a perfusion system based on a new double chamber pump. This unique design will, in theory, allow for a more complete and effective circulatory support to allow for myocardial and pulmonary recovery. The evolution from bench-top to animal testing will be described. The theoretical issues-including the advantages and disadvantages of roller and centrifugal pump designs-will also be discussed.

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“…Elle permet d'assurer un débit cardiaque, une pression de perfusion myocardique et une bonne pression aortique. Son efficacité est jugée supérieure au massage cardiaque interne [46].…”

Section: Assistance Cardio-circulatoire Percutaneeunclassified

Décès par choc anaphylactique aux curares : analyse des facteurs de risque et de la prise en charge therapeutique

Reitter

Petitpain

Latarche

et al. 2014

Annales Françaises d'Anesthésie et de Réanimation

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Extracorporeal Circulation as an Alternative to Open-Chest Cardiac Compression for Cardiac Resuscitation

Cited by 16 publications

References 30 publications

Systematic review of swine models for ventricular fibrillation induction in evaluating cardiopulmonary resuscitation methods

Systematic review of swine models for ventricular fibrillation induction in evaluating cardiopulmonary resuscitation methods

Practical and Theoretical Considerations for ECMO System Development

Décès par choc anaphylactique aux curares : analyse des facteurs de risque et de la prise en charge therapeutique

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