Extracorporeal shock wave therapy mechanisms in musculoskeletal regenerative medicine

Simplicio, Claudio Lopes; Purita, Joseph; Murrell, William; Santos, Gabriel Silva; Santos, Rafael Gonzales dos; Lana, José Fábio Santos Duarte

doi:10.1016/j.jcot.2020.02.004

Cited by 117 publications

(119 citation statements)

References 75 publications

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“…SWT memicu ekspresi adenosine triphosphate (ATP) untuk aktifasi jalur signal sel, meningkatkan permeabilitas membran sel, mobilisasi kalsium, angiogenesis, efek anti-inflamasi, merangsang makrofag dari M1 menjadi M2 sehingga merangsang mediator IL-4, IL-5, IL-9 dan IL-13. Makrofag M2 juga merangsang proliferasi sel dan perbaikan sel (31). Pada studi systematic review dan meta-analisis menunjukkan bahwa SWT memperbaiki gejala, fungsi, dan parameter elektrofisiologi penderita CTS (32).…”

Section: Shockwave Therapy (Swt)unclassified

Medical Rehabilitation Management of Carpal Tunnel Syndrome

Subadi

Hidayati²,

Fidiana³

et al. 2021

JPHV

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Carpal tunnel syndrome (CTS), the most common entrapment neuropathy in the upper extrimity, is a clinical syndrome characterized by a tingling sensation, numbness, pain, or weakness in the hand and wrist radiating up to the arm. This condition is a major cause of absenteeism, reduced productivity, and financial loss among various neuropathy due to median nerve compression. This paper, medical rehabilitation of CTS is viewed. Medical rehabilitation of CTS aimed to reduce pain, reduce clamping of the carpal tunnel, sensory and motor reeducation so that hand function improves and can perform activities of daily living. Treatment options can be given includes exercise therapy, ultrasound diathermy, low level laser therapy (LLLT), and shock wave therapy (SWT).

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Section: Shockwave Therapy (Swt)unclassified

Medical Rehabilitation Management of Carpal Tunnel Syndrome

Subadi

Hidayati²,

Fidiana³

et al. 2021

JPHV

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“…ОБРАЗЦОВ СУСТАВА ЭЛЕМЕНТАРНОЙ ФОРМЫ ПРИ УДАРНО-ВОЛНОВОМ НАГРУЖЕНИИ 1 Чирков А.О., 2 Еремина Г.М., Смолин А.Ю., 2 Еремин М.О. 1 Томский государственный университет, Томск 2 Институт физики прочности и материаловедения СО РАН, Томск Ударно-волновая терапия стала применятся для лечения несращиваемых переломов и ускорения процессов заживления переломов с конца 20 века [1]. Главной характеристикой ударно-волнового процесса в биомедициннских целях является плотность потока энергии (EFD-energy fleux density).…”

Section: Doi: 1017223/978-5-907442-03-0-2021-382 численное исследование механического поведения модельныхunclassified

“…В настоящее время ведутся активные исследования по определению оптимальных параметров нагружения способствующих регенерации костных и хрящевых тканей. По данным [2] низкоэнергетической считается нагрузка до EFD = 0.08 мДж/мм 2 , среднеэнергетической до 0.2 мДж/мм 2 , и выcокоэнергетической применяемой для регенерации биологических тканей до 0.9 мДж/мм 2 . Большинство авторов приводят практически одинаковое диапазоны напряженно-деформируемого состояния способствующего регенеративным процессам в костных и хрящевых тканях [3].…”

Section: Doi: 1017223/978-5-907442-03-0-2021-382 численное исследование механического поведения модельныхunclassified

Численное Исследование Механического Поведения Модельных Образцов Сустава Элементарной Формы При Ударно-Волновом Нагружении

2021

Международная Конференция "Физическая Мезомеханика. Материалы С Многоуровневой Иерархически Организованной Структурой И Интелле

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“…Extracorporeal shock wave (ESW), a short duration acoustic wave that carry energy and can propagate through soft tissues, is a cost-effective and non-invasive modality, which is widely used in clinic for the treatment of various diseases, mainly including renal calculus, erectile dysfunction, and musculoskeletal disorder (1)(2)(3). It is believed that Extracorporeal shock wave therapy (ESWT) has positive effects on wound healing, angiogenesis, tissue regeneration, and bone remodeling via physical interaction (4,5). A growing number of studies demonstrated that ESWT has shown promising outcomes in the treatment of fracture, osteonecrosis, osteoarthritis, as well as osteoporosis (3,6,7).…”

Section: Introductionmentioning

confidence: 99%

Extracorporeal Shock Wave Therapy Promotes Osteogenic Differentiation in a Rabbit Osteoporosis Model

Wang

Huang

et al. 2021

Front. Endocrinol.

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Extracorporeal shock wave therapy (ESWT) has been identified to accelerate bone formation. However, detailed mechanism has not been fully explained. In this study, we found that ESWT promoted osteoblast formation in vitro. Local ESW treatment of femur increased bone formation in vivo. Furthermore, changing the density or frequency of energy, there was no statistical difference in osteogenic differentiation. Therapeutically, local ESW therapy relieved bone loss and increased the number of bone trabecular in a rabbit osteoporosis model and promoted endogenous levels of SMAD2 protein expression. Thus, ESWT may be a potential therapy by promoting osteoblast maturation through TGF-β/SMAD2 pathway.

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Extracorporeal shock wave therapy mechanisms in musculoskeletal regenerative medicine

Cited by 117 publications

References 75 publications

Medical Rehabilitation Management of Carpal Tunnel Syndrome

Medical Rehabilitation Management of Carpal Tunnel Syndrome

Численное Исследование Механического Поведения Модельных Образцов Сустава Элементарной Формы При Ударно-Волновом Нагружении

Extracorporeal Shock Wave Therapy Promotes Osteogenic Differentiation in a Rabbit Osteoporosis Model

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