Extracorporeal Worm Extraction of Diphyllobothrium nihonkaiense with Amidotrizoic Acid in a Child

Abstract

Infection cases of diphyllobothriid tapeworms are not much in the below teen-age group. We report a case of Diphyllobothrium nihonkaiense infection in a 13-year-old boy. He presented with severe fatigue, occasional abdominal pain at night time. He also had several episodes of tapeworm segment discharge in his stools. By his past history, he had frequently eaten raw fish including salmon and trout with his families. Numerous eggs of diphyllobothriid tapeworm were detected in the fecal examination. We introduced amidotrizoic acid as a cathartic agent through nasogastroduodenal tube and let nearly whole length (4.75 m) of D. nihonkaiense be excreted through his anus. After a single dose of praziquantel, the child's stool showed no further eggs, and his symptoms disappeared. The evacuated worm was identified as D. nihonkaiense by mitochondrial cox1 gene analysis. Here we report a successful extracorporeal worm extraction from an infection case of D. nihonkaiense by the injection of amidotrizoic acid.

Diphyllobothrium nihonkaiense: wide egg size variation in 32 molecularly confirmed adult specimens from Korea

“…Thereafter, approximately 110 cases of Diphyllobothrium sp. infection were documented, and the number of case reports has increased recently Jeon et al 2009;Park et al 2013;Song et al 2014;Kim et al 2014;Shin et al 2014). D. nihonkaiense was first characterized by molecular studies of the parasite gene in Korea (Jeon et al 2009).…”

“…Infection with the latter species is reportedly on the rise in Asia, including Japan (Arizono et al 2009a), China (Chen et al 2014), and South Korea (= Korea) (Jeon et al 2009;Park et al 2013;Song et al 2014;Kim et al 2014;Shin et al 2014). Sporadic infections with D. nihonkaiense were also detected in Europe (Yera et al 2006;Wicht et al 2007), America (Wicht et al 2008), and New Zealand (Yamasaki and Kuramochi 2009), possibly due to an increased global consumption of pacific salmon, the major source of D. nihonkaiense infection (Arizono et al 2009a).…”

“…The annual clinical incidence of D. nihonkaiense infection in two Japanese institutions in Tokyo and Kyoto showed an apparent surge in the recent years (Arizono et al 2009a). Similarly, in Korea, D. nihonkaiense cases have also been on the rise since 2013 (Park et al 2013;Song et al 2014;Kim et al 2014;Shin et al 2014). Fig.…”

Diphyllobothriidae

“…In Korea, using genetic probes around 77 cases of D. nihonkaiensis have been identified since 1998 (Jeon et al, 2009;Kim et al, 2014;Shin et al, 2014;Song et al, 2014;Choi et al, 2015;Go et al, 2015;Park et al, 2015).…”