Extracting trace amount of terbinafine hydrochloride in biological fluids and wastewater samples using solid‐phase‐extraction based on magnetic nanoparticles followed by HPLC‐UV analysis

Abbasi, Laleh; Faraji, Mohammad; Bahmaie, M.

doi:10.1002/apj.1830

Cited by 4 publications

(4 citation statements)

References 36 publications

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“…The maximum removal of TRB HCl was achieved at 20 and 100 ppm concentrations of TRB HCl by CS and PUF, respectively. In a previous study on removing TRB HCl using sodium dodecylsulfate-coated Fe3O4 nanoparticles 60 , the calibration curve was linear within the range of 0.0025 to 0.5 ppm.…”

Section: Effect Of Drug Capacitymentioning

confidence: 89%

“…In a previous study by Abbasi L. et al 60 on removing TRB HCl from sodium dodecyl sulfate-coated Fe3O4 nanoparticles, the optimum adsorption was achieved at a pH of 2.0.…”

Section: Effect Of Phmentioning

confidence: 95%

“…These results indicate that the optimum exposure period is 60 min for the removal by both sorbents. In a previous study on removing TRB HCl using sodium dodecylsulfate-coated Fe3O4 nanoparticles 60 , a period of 1 min was found to be an optimal sorption time.…”

Section: Effect Of Contact Timementioning

confidence: 99%

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Elimination of Terbinafine Hydrochloride Antifungal Drug Traces from Water, Pharmaceutical Formulations and Blood Plasma using Low-Cost Bio and Synthetic Sorbents

2022

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: Chitosan (CS) biosorbent and polyurethane foam (PUF) synthetic sorbent have been utilized to eliminate terbinafine hydrochloride (TRB HCl) antifungal drug in its pure and pharmaceutical forms from both contaminated aqueous and biological media using a batch process. The experimental conditions for efficient removal of TRB HCl for both CS and PUF were optimized depending on various experimental parameters such as the pH of the solution, contact periods, initial TRB HCl concentration, and sorbents dosage in the solution.SEM, FT-IR, and XRD characterizations were carried out to study the adsorption of a drug by both sorbents. The optimum conditions for removing TRB HCl by CS and PUF were achieved at a pH of 8.5 and a contact time of 60 min at 250 rpm, using 0.4 g for both sorbents. The measured spectrophotometric absorbance at λmax of TRB HCl was 242 nm. In addition, the zero-point charge (pHpzc) was determined for the studied sorbents. The pHpzc of the surface of sorbents has shown that electrostatic attraction is one of the mechanisms in TRB HCl sorption. The adsorption process was modeled using the pseudo-first-order, pseudo-second-order, Elovich, and intraparticle diffusion kinetic models. The results indicated that the adsorption of TRB HCl on CS and PUF does follow a pseudo-first-order type of reaction kinetics. The adsorption process was modeled using Langmuir and Freundlich isotherms. The adsorption data found that the Freundlich isotherm model was more suitable for the PUF sorbent, while the Langmuir isotherm model better fit the CS biosorbent.Evaluation of the experimental data using the Langmuir equation revealed that the maximum adsorption capacities of PUF and CS were 2.807 and 1.2297 mg. g-1, respectively. The solution was also used to estimate TRB HCl in its pharmaceutical form, and the assessed recoveries were 97.25 and 98.437% for CS and PUF, respectively. The proposed procedure was validated for other complex mediums by removing TRB HCl from spiked human blood plasma. In-silico aquatic toxicity forecast of TRB HCl was also carried out.

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Section: Effect Of Drug Capacitymentioning

confidence: 89%

“…In a previous study by Abbasi L. et al 60 on removing TRB HCl from sodium dodecyl sulfate-coated Fe3O4 nanoparticles, the optimum adsorption was achieved at a pH of 2.0.…”

Section: Effect Of Phmentioning

confidence: 95%

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Elimination of Terbinafine Hydrochloride Antifungal Drug Traces from Water, Pharmaceutical Formulations and Blood Plasma using Low-Cost Bio and Synthetic Sorbents

2022

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“…Moreover, in this study, the potential of DDAB in NP functionalization is exploited to develop a novel Fe 3 O 4 -based microsampling protocol. This marks the first documentation of such a procedure, as the application of surfactants has strictly been limited to single-chain structures, mainly cetyltrimethylammonium bromide (CTAB) and sodium dodecyl sulfate (SDS), in previous works [15,[20][21][22].…”

Section: Amount Of Ddabmentioning

confidence: 99%

Magnetic Solid-Phase Microextraction Protocol Based on Didodecyldimethylammonium Bromide-Functionalized Nanoparticles for the Quantification of Epirubicin in Biological Matrices

et al. 2023

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Due to epirubicin’s (EPI) narrow therapeutic index and risk of cardiotoxicity, it is critical to monitor concentrations of this drug when being used to treat cancer patients. In this study, a simple and fast magnetic solid-phase microextraction (MSPME) protocol for the determination of EPI in plasma and urine samples is developed and tested. Experiments were performed using prepared Fe3O4-based nanoparticles coated with silica and a double-chain surfactant—namely, didodecyldimethylammonium bromide (DDAB)—as a magnetic sorbent. All the prepared samples were analyzed via liquid chromatography coupled with fluorescence detection (LC-FL). The validation parameters indicated good linearity in the range of 0.001–1 µg/mL with a correlation coefficient > 0.9996 for plasma samples, and in the range of 0.001–10 µg/mL with a correlation coefficient > 0.9997 for urine samples. The limit of detection (LOD) and limit of quantification (LOQ) for both matrices were estimated at 0.0005 µg/mL and 0.001 µg/mL, respectively. The analyte recovery after sample pretreatment was 80 ± 5% for the plasma samples and 90 ± 3% for the urine samples. The developed method’s applicability for monitoring EPI concentrations was evaluated by employing it to analyze real plasma and urine samples collected from a pediatric cancer patient. The obtained results confirmed the proposed MSPME-based method’s usefulness, and enabled the determination of the EPI concentration–time profile in the studied patient. The miniaturization of the sampling procedure, along with the significant reduction in pre-treatment steps, make the proposed protocol a promising alternative to routine approaches to monitoring EPI levels in clinical laboratories.

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Evaluation of synergistic adsorption approach for terbinafine removal by cotton shell powder immobilized zerovalent copper: Adsorption kinetics and DFT simulation

Kaur,

Hussain,

Kumar

et al. 2023

Environmental Nanotechnology, Monitoring & Management

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Extracting trace amount of terbinafine hydrochloride in biological fluids and wastewater samples using solid‐phase‐extraction based on magnetic nanoparticles followed by HPLC‐UV analysis

Cited by 4 publications

References 36 publications

Elimination of Terbinafine Hydrochloride Antifungal Drug Traces from Water, Pharmaceutical Formulations and Blood Plasma using Low-Cost Bio and Synthetic Sorbents

Elimination of Terbinafine Hydrochloride Antifungal Drug Traces from Water, Pharmaceutical Formulations and Blood Plasma using Low-Cost Bio and Synthetic Sorbents

Magnetic Solid-Phase Microextraction Protocol Based on Didodecyldimethylammonium Bromide-Functionalized Nanoparticles for the Quantification of Epirubicin in Biological Matrices

Evaluation of synergistic adsorption approach for terbinafine removal by cotton shell powder immobilized zerovalent copper: Adsorption kinetics and DFT simulation

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