Extraction, characterization and antitumor effect of the polysaccharides from star anise (Illicium verum Hook. f.)

Shu, Xin; Liu, Xiongmin; Fu, Chunlin; Liang, Qiu‐Xia

doi:10.5897/jmpr09.438

Cited by 18 publications

(3 citation statements)

References 25 publications

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“…This is attributed to its demonstrated effectiveness in antimicrobial, antifungal, and antioxidant activities (Benmalek et al., 2013; Chouksey & Sharma, 2010). Star anise reportedly is utilized in treatment of various diseases, such as infantile colic and metastatic cancer (Li & Xu, 2020; Shu et al., 2010). Additionally, a promising COVID‐19 main protease inhibitor was identified from star anise (Tripathi et al., 2022).…”

Section: Discussionmentioning

confidence: 99%

Exploring the pharmacological mechanisms of star anise against COVID‐19 using network pharmacology and molecular docking

Li,

Gao,

Liu

et al. 2024

Food Safety and Health

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Traditional Chinese Medicine (TCM) has exhibited promising preventive and therapeutic attributes against COVID‐19. This study aims to investigate the active constituents within star anise and elucidate their mechanisms in combatting COVID‐19, employing a combination of GC‐MS analysis, network pharmacology, and molecular docking techniques. Various extraction methods were employed to obtain star anise compounds, which were subsequently subjected to GC‐MS analysis. A comprehensive star anise and COVID‐19‐related genomic network was established through Swiss Target Prediction and disease‐gene databases. Network pharmacology analysis unveiled the significant prominence of common core targets, namely TLR4, PTGS2, RELA, and ESR1. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses revealed that star anise may exert its preventive effects against COVID‐19 by modulating immune responses, apoptosis, and viral infections. Molecular docking investigations provided compelling evidence of substantial interactions between the active compounds found in star anise and the key target proteins. In summary, this work has the potential to offer new avenues and a theoretical foundation for a more in‐depth understanding of the multicomponents, multitarget, and multipathway properties of star anise in preventing COVID‐19.

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Section: Discussionmentioning

confidence: 99%

Exploring the pharmacological mechanisms of star anise against COVID‐19 using network pharmacology and molecular docking

Li,

Gao,

Liu

et al. 2024

Food Safety and Health

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“…The extracted shikimic acid is one of the main ingredients of the antiviral drug Tamiflu ® (oseltamivir) that is used to treat symptoms caused by avian influenza [98]. It has also been reported to have antimicrobial properties [99] and antioxidant properties [100], as well as significant anti-cancer potential [101]. There are studies in which star anise has been used as an insect repellent, such as for the Indian flour moth (P. interpunctella larvae) [102,103].…”

Section: Essential Oils In Plantsmentioning

confidence: 99%

Microencapsulation of Essential Oils: A Review

et al. 2022

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Essential oils (EOs) are complex mixtures of volatile compounds extracted from different parts of plants by different methods. There is a large diversity of these natural substances with varying properties that lead to their common use in several areas. The agrochemical, pharmaceutical, medical, food, and textile industry, as well as cosmetic and hygiene applications are some of the areas where EOs are widely included. To overcome the limitation of EOs being highly volatile and reactive, microencapsulation has become one of the preferred methods to retain and control these compounds. This review explores the techniques for extracting essential oils from aromatic plant matter. Microencapsulation strategies and the available technologies are also reviewed, along with an in-depth overview of the current research and application of microencapsulated EOs.

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“…Modern pharmacological investigations demonstrated that I. verum possessed antiviral, , antioxidant, , antitumor, , antibacterial, , insecticidal, , anti-inflammatory, , analgesic, and neuroprotective activities. Previous phytochemical studies on I.…”

Section: Introductionmentioning

confidence: 99%

Antiviral and Antioxidant Components from the Fruits of Illicium verum Hook.f. (Chinese Star Anise)

Xia

et al. 2022

J. Agric. Food Chem.

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Illicium verum Hook.f. (Chinese star anise), a known Chinese traditional spice, is commonly applied in Chinese cuisine and cooking in Southeast Asia. As a kind of medicinal and edible resource, the fruit of I. verum has attracted great attention for its chemical constituents and physiological activities. In this work, the phytochemical study of the fruits of I. verum led to the isolation and identification of 20 compounds, including 6 new lignans and phenylpropanoids (1–6) and 14 known ones (7–20). Their structures were characterized by extensive analysis of spectroscopic data (IR, UV, high-resolution electrospray ionization mass spectrometry (HR-ESI-MS), one-dimensional (1D) and two-dimensional (1D) NMR), electronic circular dichroism (ECD) calculation, and by comparison with literature data. Meanwhile, all compounds (1–20) were evaluated for their antiviral and antioxidant activities. Especially, compound 7 [(−)-bornyl p-coumarate] showed strong antiviral activities against influenza virus A/Puerto Rico/8/34 H1N1 (PR8) with an IC50 value of 1.74 ± 0.47 μM, which is much better than those of Tamiflu (IC50 = 10.01 ± 0.92 μM) and ribavirin (IC50 = 10.76 ± 1.60 μM). The antiviral activity against PR8 of compound 7 was reported for the first time, which was sufficiently confirmed by cell counting kit 8 (CCK-8), cytopathic effect (CPE) reduction, and immunofluorescence assays. In this study, the discovery of antiviral and antioxidant components from the fruits of I. verum could benefit the further development and utilization of this plant.

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Extraction, characterization and antitumor effect of the polysaccharides from star anise (Illicium verum Hook. f.)

Abstract: Polysaccharides production from star anise was carried out. The effects of extraction temperature, time, ratio of water to raw material and number of extraction were optimized by using an orthogonal L9 (

Cited by 18 publications

References 25 publications

Exploring the pharmacological mechanisms of star anise against COVID‐19 using network pharmacology and molecular docking

Exploring the pharmacological mechanisms of star anise against COVID‐19 using network pharmacology and molecular docking

Microencapsulation of Essential Oils: A Review

Antiviral and Antioxidant Components from the Fruits of Illicium verum Hook.f. (Chinese Star Anise)

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