Extraction, characterization, haematocompatibility and antioxidant activity of linseed polysaccharide

Mohanta, Bulu; Sen, Dhrubo Jyoti; Mahanti, Beduin; Nayak, Amit Kumar

doi:10.1016/j.carpta.2023.100321

Cited by 6 publications

(2 citation statements)

References 42 publications

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“…Mucilage was successfully obtained from brown flax seeds and after basic characterization studies such as yield, ash content, moisture content, chemical structure, and surface charge, the characteristics of the material were identified. The yield is in the range of yield values (4.50%-20.77% by weight) obtained in other studies on mucilage extraction from flax seed [18,[39][40][41][42]. The ash content agrees with the results of Kaur et al who determined the ash content of six different varieties of Indian flax seeds in the range of 4.80%-7.23% [2].…”

Section: Discussionsupporting

confidence: 87%

Potential use of extracted flax seed mucilage in the construction of macroporous cryo-scaffolds

Demir

2024

Biomed. Mater.

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Mucilage is a natural source of polysaccharides that has recently attracted attention for use in biomaterial production. It attracts attention with its easy and fast extraction, biocompatibility, high water retention capacity, and biodegradability. Although there are studies on the characterization of mucilage obtained from different plant sources, the interaction of this polymer with other polymers and its potential to form new biomaterials have not yet been sufficiently investigated. Based on this, in this study, the potential of mucilage extracted from flaxseed for the production of cryogels for tissue engineering applications was demonstrated. Firstly, yield, basic physicochemical properties, morphology, and surface charge-dependent isoelectric point determination studies were carried out for the characterization of the extracted mucilage. The successful preparation of mucilage was evaluated for the construction of cryo-scaffolds and 3D, spongy, and porous structures were obtained in the presence of chitosan and polyvinyl alcohol polymers. A heterogeneous morphology with interconnected macro and micro porosity in the range of approximately 85–115 m pore diameter was exhibited. Due to the high hydrophilic structure of the mucilage, which is attached to the structure with weak hydrogen bonds, the contact angle values of the scaffolds were obtained below 80° and they showed the ability to absorb 1000 times their dry weight in approximately 30 min. As a preliminary optimization study for the evaluation of mucilage in cryogel formation, this work introduced a new construct to be developed as wound dressing scaffold for deep and chronic wounds.

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Section: Discussionsupporting

confidence: 87%

Potential use of extracted flax seed mucilage in the construction of macroporous cryo-scaffolds

Demir

2024

Biomed. Mater.

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“…These findings indicate that the fucoidan-fortified CSB exhibited significant DPPH• radical scavenging activity and ABTS• radical scavenging activity. One possible explanation for the enhanced scavenging activity of polysaccharide is that the ability of polysaccharides to provide protons reduces the stable DPPH• radical to diphenylpicryl hydrazine (a type of yellow compound) and that the polysaccharide also could convert the ABTS• to a non-radical form by providing electrons [60,61]. Another plausible explanation is that the fucoidan was exposed to more sulphates during the dough fermentation process, so the antioxidant activity of the CSB was enhanced [10,15].…”

Section: Antioxidant Activity Of Csb Analysismentioning

confidence: 99%

Effect of Fucoidan on Structure and Bioactivity of Chinese Steamed Bread

Yang,

Li,

et al. 2024

Foods

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Fucoidan refers to a group of sulphated polysaccharides obtained from brown seaweed, with numerous biological activities. In this study, fucoidan was fortified into Chinese steamed bread (CSB) at different concentrations (0, 1%, 3% and 5%) and the effect of fucoidan on the dough properties, structure properties and bioactivity were investigated. The results showed that fucoidan could change the viscosity of unfermented dough, and a high concentration of fucoidan could remove the free radicals produced by the SH–SS exchange reaction (GS-) in the dough, which significantly reduced the content of disulfide bond and reduced the expanded volume of fermented dough (p < 0.05). In addition, fucoidan forms a physical barrier on the surface of starch particles and hinders the reaction between protein-to-protein; therefore, fucoidan increased the hardness, gumminess and chewiness in CSB, and reduced the specific volume in CSB. Furthermore, the fucoidan-fortified CSB samples were found to have both the ability to significantly reduce the predicted glycemic index (pGI) (p < 0.05) and improve antioxidant activity (p < 0.05). Collectively, these findings could provide a theoretical basis for the applications of fucoidan as a functional component in fermented foods.

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Extraction, Characterization, Biocompatibility, and Antioxidant Activity of Dillenia Indica L. Fruit Polysaccharide

Mohanta,

Sen,

Nayak

2024

Starch Stärke

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The current investigation describes extraction and characterization of aqueous‐soluble polysaccharide (DIFP) from mature Dillenia indica L., fruits to explore its biocompatibility and antioxidant properties (in vitro). In this work, employing the hot‐water extraction method, a whitish brown colored, tasteless, odorless DIFP is extracted (14.45% yield). The findings of the phytochemical identification showed that the extracted DIFP contained both mucilage and carbohydrates. The purity of DIFP is revealed by the examination of three different ash values. 1H NMR spectroscopy, FT‐IR spectroscopy, DSC, and P‐XRD analyses of extracted DIFP are carried out. The results of hemocompatibility (in vitro) experiments, in particular, the determinations of hemolysis percentage (0.80%) and thrombogenicity percentage (5.55%), indicated that the DIFP exhibited nonhemolytic and nonthrombogenic properties. The in vivo acute toxicity evaluation in Swiss Albino male mice clearly presented the absence of any mortality (within 24 h) after intraperitoneal administration of the extracted DIFP (up to 1500 mg kg−1), indicating its nontoxicity, in vivo. Different in vitro tests of antioxidant activity, such as DPPH, ABTS, and hydroxyl radical scavenging, showed a strong antioxidant effect of extracted DIFP. The extracted DIFP (from mature DIFs by hot‐water extraction method) can be used as a natural antioxidant in a variety of applications.

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Extraction, characterization, haematocompatibility and antioxidant activity of linseed polysaccharide

Cited by 6 publications

References 42 publications

Potential use of extracted flax seed mucilage in the construction of macroporous cryo-scaffolds

Potential use of extracted flax seed mucilage in the construction of macroporous cryo-scaffolds

Effect of Fucoidan on Structure and Bioactivity of Chinese Steamed Bread

Extraction, Characterization, Biocompatibility, and Antioxidant Activity of Dillenia Indica L. Fruit Polysaccharide

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