2017
DOI: 10.1016/j.supflu.2016.12.012
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Extraction of bioactive alkaloids from Melocactus zehntneri using supercritical fluid

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Cited by 12 publications
(4 citation statements)
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“…These compounds are particularly active against drug-resistant strains of Plasmodium falciparum [ 72 ]. Melocactus zehntneri is a medicinal cactus that is unusual pharmacologically because it contains isoquinoline and indole alkaloids, which are used in several drugs [ 128 ].…”
Section: Current Applications Of Supercritical Fluid Extractionmentioning
confidence: 99%
“…These compounds are particularly active against drug-resistant strains of Plasmodium falciparum [ 72 ]. Melocactus zehntneri is a medicinal cactus that is unusual pharmacologically because it contains isoquinoline and indole alkaloids, which are used in several drugs [ 128 ].…”
Section: Current Applications Of Supercritical Fluid Extractionmentioning
confidence: 99%
“…SFE with water and/or alcohols (ethanol or methanol) as cosolvents have been used for alkaloid extraction to modify the polarity of the scCO 2 solvent and enhance the extraction efficiency due to the extended solvating strength for alkaloids. [100][101][102][103][104][105][106][107][108][109][110] Co-solvents like ethanol, methanol, propylene glycol, and 1,2-propanediol are important to extract high yields of alkaloids. Usually, co-solvents are employed at concentrations below 10% of the amount of scCO 2 .…”
Section: Supercritical Fluid Extraction Of Alkaloidsmentioning
confidence: 99%
“…104 Liu et al 117 reported an increase of 41% in the alkaloid yield extracted from the rhizome of Corydalis yanhusuo by increasing the temperature from 50 to 70 °C. On the contrary, Brandão et al 104 showed a decrease in the extraction of alkaloid from the young raw material of the Melocactus zehntneri plant due to an increase in temperature (35 to 55 °C) during SFE, which was related to a decrease in scCO 2 density. Similarly, Carrara et al 119 increased alkaloid extraction from 0.96 mg g −1 at 50 °C to 2.0 mg g −1 at 40 °C.…”
Section: Supercritical Fluid Extraction Of Alkaloidsmentioning
confidence: 99%
“…Estudos envolvendo M. zehntneri vêm sendo desenvolvidos especialmente quanto aos seus aspectos etnobotânicos (CHAVES; BARROS, 2015;LUCENA et al, 2015) ou com enfoque farmacológico, com o objetivo de identificar e quantificar compostos bioativos (NUNES et al, 2016;BRANDÃO et al, 2016). Devido ao considerável grau de ameaça sofrido por esta espécie, ocasionado pela degradação de seus habitats e pela coleta e comércio ilegal, bem como pelo seu valor ornamental e pelo fato de não apresentar emissão de brotamentos quando em condições naturais, há um crescente interesse em ações de conservação e em estudos de propagação da mesma.…”
Section: Melocactus Zehntneriunclassified