2021
DOI: 10.1016/j.ifset.2021.102697
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Extraction of bioactive compounds from Curcuma longa L. using deep eutectic solvents: In vitro and in vivo biological activities

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Cited by 37 publications
(14 citation statements)
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“…The highlight was the extract sample with C. citratus (180 min of magnetic stirring), and the pure DES sample ([Ch]Cl:AA) was tested and did not show any iron chelating activity, therefore, the activity found is due to the compounds extracted from the lemon grass C. citratus . An activity of 33% is substantial and this fact stood out some possibilities to apply this DES‐based plant extract: Pharmaceutical, medical, and food industries value metal chelating activities (Oliveira et al, 2021; Viuda‐Martos et al, 2010). DES‐based extracts have been tested already as extractors of heavy metals for metal determinations on food samples, milk, and fish, (Haq et al, 2021; Sorouraddin, Farajzadeh, & Dastoori, 2020) personal pharmaceutical care (Wei et al, 2020), and medical, as the extraction of RNA (Meng et al, 2020).…”
Section: Resultsmentioning
confidence: 99%
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“…The highlight was the extract sample with C. citratus (180 min of magnetic stirring), and the pure DES sample ([Ch]Cl:AA) was tested and did not show any iron chelating activity, therefore, the activity found is due to the compounds extracted from the lemon grass C. citratus . An activity of 33% is substantial and this fact stood out some possibilities to apply this DES‐based plant extract: Pharmaceutical, medical, and food industries value metal chelating activities (Oliveira et al, 2021; Viuda‐Martos et al, 2010). DES‐based extracts have been tested already as extractors of heavy metals for metal determinations on food samples, milk, and fish, (Haq et al, 2021; Sorouraddin, Farajzadeh, & Dastoori, 2020) personal pharmaceutical care (Wei et al, 2020), and medical, as the extraction of RNA (Meng et al, 2020).…”
Section: Resultsmentioning
confidence: 99%
“…This procedure was applied to the three lemongrass species, in triplicate, totaling 72 samples. To select the optimal solvents, antioxidant activity analysis (DPPH and FRAP) and TPC were employed (Leal et al, 2022; Oliveira et al, 2021).…”
Section: Methodsmentioning
confidence: 99%
“…Temperature of 45 ◦C showed the best performance. ------ [185] Phenolic compounds Onion, olive, tomato and pear industrial by-products UAE ES: NADES (LGH) A sample material/solvent ratio of 75 mg mL − 1 sonicated (USB) at 200 W output power, 20 kHz frequency, during 60 min ------ [186] Phenolic compounds Argentinian autochthonous plant (Larrea cuneifolia) UAE ES: NADES (LGH) A sample material/solvent ratio of 75 mg mL − 1 sonicated (USB) at 200 W output power, 20 kHz frequency, during 42 min Reduce the use of organic solvents, Improved sample throughput [187] Phenolic compounds Lactuca sativa UA-NADES ES: NADES (LGH) 248.5 mg of lyophilized lettuce samples, 7 mL of LGH, sonicated (USB) 36 min at 200 W, 20 kHz ------ [188] Free seleno-amino acids Lyophilized and powdered milk UAE ES: NADES (LGH) 0.94 g of homogenized milk sample, 3.09 mL of LGH sonicated (USB) for 34 min ----- [189] Antioxidant compounds, sulforaphane and fatty acids Papaya seeds (Vasconcellea pubescens) UAE ES: 80% aqueous methanol 5 g of seeds, solid/liquid ratio of 1:2, sonicated (USB) 42 kHz, 130 W for 15 min. Low energy requirements Low solvent consumption Enhanced solvent penetration into plant materials.…”
Section: Ultrasound-assisted Analytical Methodsmentioning
confidence: 99%
“…The same analytes were extracted from rhizome, leaves, and flowers of Curcuma longa by Oliveira et al . in a collaborative development between Brazil and Portugal [185] , using a hydrophobic deep eutectic solvent based on menthol and choline chloride. In comparison with the traditional solvent (ethanol), the hydrophobic DES evaluated presented higher extraction yields.…”
Section: Ultrasound-assisted Analytical Methodsmentioning
confidence: 99%
“…Therefore, it is useful to use NDES for the extraction of active compounds. The use of NDES can prevent solubility problems of compounds, which increases the bioactivity of substances [ 23 , 24 ]. For example, cinnamon contains a number of active compounds such as cinnamaldehyde and polyphenols, i.e., bioactive compounds that have anti-cancer, anti-inflammatory, anti-diabetic, hyperglycaemic, and antioxidant properties.…”
Section: Introductionmentioning
confidence: 99%