Extraction of bioactives from fruit and vegetables: State of the art and perspectives

Renard, Catherine M.G.C.

doi:10.1016/j.lwt.2018.03.063

Cited by 88 publications

(43 citation statements)

References 48 publications

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“…The important challenge in the recovery of phenolic compounds from fruits waste is the choice of the solvent used, which must meet the REACH characteristics (Registration, Evaluation, Authorization and Restriction of Chemicals regulation) (Renard, 2018). Bio-based solvents, subcritical liquids, ionic liquids or (natural) deep eutectic solvents are now often used (Radosevic et al, 2016;Lima et al, 2017;Ozturk et al, 2018).…”

Section: Production Of Active Principles From Fruit By-productsmentioning

confidence: 99%

Fruits By-Products – A Source of Valuable Active Principles. A Short Review

Fierăscu

Sieniawska

Orţan

et al. 2020

Front. Bioeng. Biotechnol.

111

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The growing demand for more sustainable, alternative processes leading to production of plant-derived preparations imposes the use of plants waste generated mainly by agri-food and pharmaceutical industries. These mostly unexploited but large quantities of plants waste also increase the interest in developing alternative approaches for sustainable production of therapeutic molecules. In order to reduce the amount of plant waste by further processing, different novel extraction techniques can be applied. Fruits and their industrial by-products are rich sources of different classes of compounds with therapeutic properties. The processed fruits waste can be reused and lead to novel pharmaceuticals, food supplements or functional foods. This review intends to briefly summarize recent aspects regarding the production of different active compounds from fruit by-products, and their therapeutic properties. The potential use of fruits by-products in different industries will be also discussed.

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Section: Production Of Active Principles From Fruit By-productsmentioning

confidence: 99%

Fruits By-Products – A Source of Valuable Active Principles. A Short Review

Fierăscu

Sieniawska

Orţan

et al. 2020

Front. Bioeng. Biotechnol.

111

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“…Supercritical CO 2 (ScCO 2 ) is also attractive because of its high diffusivity and its easily tunable solvent strength. It is possible to obtain ScCO 2 at 304.2 K and 7.39 MPa [15,53].…”

Section: Supercritical-fluid Extraction (Sfe)mentioning

confidence: 99%

Trends and Challenges in the Industrialization of Natural Colorants

Neves¹,

Silva²,

Meireles³

2019

fph

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Consumer demands and their preferences for naturally derived colorants have increased exponentially and are widely associated with the image of healthy, safe and high-quality products, which constitutes a great challenge to food industries and related food science research institutions. Moreover, such demands have resulted in searches to increase the availability of these compounds. Despite the intense search for plant and microbial sources and efforts to increase extraction yield, few natural colorants have reached available the market. Physicochemical instability during the extraction and storage of natural colorants is a major limitation; some non-conventional extraction and encapsulation technologies are being advocated to minimize this problem. Thus, improving the techniques used for the encapsulation of sensitive or labile ingredients is important to make colorants and, consequently, their bioactive proprieties, accessible to consumers.

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“…physostigmine was isolated from Physostigma venenosum and its chemical molecular base provided a template for the development of rivastigmine improving the pharmacokinetic parameters and efficacy . Thus, plants and fruits have demonstrated to be a relevant source of bioactive compounds that could contribute to reduce the risk of suffering or treat some degenerative diseases . Annona cherimola Mill.…”

Section: Introductionmentioning

confidence: 99%

“…4,5 Thus, plants and fruits have demonstrated to be a relevant source of bioactive compounds that could contribute to reduce the risk of suffering or treat some degenerative diseases. 6 Annona cherimola Mill. (cherimoya) is a tropical fruit with exceptional taste and strong antioxidant activity attributed to its phenolic content.…”

mentioning

confidence: 99%

Detection and identification of acetylcholinesterase inhibitors in Annona cherimola Mill. by effect‐directed analysis using thin‐layer chromatography‐bioassay‐mass spectrometry

Galarce‐Bustos

Pavón

Henriquez‐Aedo

et al. 2019

Phytochemical Analysis

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Introduction Acetylcholinesterase (AChE) inhibitors are considered an important strategy in the treatment of neurological disorders such as Alzheimer's disease. A simple and fast planar chromatography‐bioassay methodology has been established to detect bioactive molecules in cherimoya fruit. Objective Detect and identify AChE inhibitors in cherimoya by high‐performance thin‐layer chromatography (HPTLC)‐bioassay‐mass spectrometry (MS) and related techniques. Methodology Effect‐directed analysis by planar chromatography‐bioassay‐mass spectrometry was applied to detect and identify AChE inhibitors in pulp, peel and cherimoya seed. Bioassay was optimised establishing the following conditions: enzymatic solution (1.0 U mL−1), 1‐naphtyl acetate substrate (1.5 mg mL−1) and Fast Blue B salt (1.0 mg mL−1). TLC‐MS interface was used to directly elute the active zones into a mass spectrometer or to a micro‐vial for further off‐line studies. Results Two AChE inhibitory bands were detected in peel extracts. An analysis via HPTLC‐MS and high‐performance liquid chromatography diode array detector tandem mass spectrometry (HPLC‐DAD‐MS/MS) allowed to characterise three potential AChE inhibitors: anonaine (m/z 266 [M + H]+; UV λmax = 269.6 nm), glaucine (m/z 256 [M + H]+; UV λmax = 282.9 and 300.6 nm) and xylopine (m/z 296 [M + H]+; UV λmax = 278.5 nm). Conclusions The application of this optimised high throughput method allowed to establish the presence of three potential AChE inhibitors in cherimoya peel. For the first time AChE inhibitory capacity of these alkaloids is reported.

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Extraction of bioactives from fruit and vegetables: State of the art and perspectives

Cited by 88 publications

References 48 publications

Fruits By-Products – A Source of Valuable Active Principles. A Short Review

Fruits By-Products – A Source of Valuable Active Principles. A Short Review

Trends and Challenges in the Industrialization of Natural Colorants

Detection and identification of acetylcholinesterase inhibitors in Annona cherimola Mill. by effect‐directed analysis using thin‐layer chromatography‐bioassay‐mass spectrometry

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