Extraction of curcumin from turmeric residue (Curcuma longa L.) using deep eutectic solvents and surfactant solvents

Abstract

An efficient choline chloride-based DES method is used to extract curcumin in turmeric residue for the first time.

Antioxidant, Anti‐Skin‐Aging, Anti‐Inflammatory, and Anti‐Acetylcholinesterase Activities of Rourea oligophlebia Extracts

“…All the extracts were tested for anti‐AChE activity using the Ellman method. Acetylthiocholine iodide is hydrolyzed by the enzyme AChE to form thiocholine, which then reacts with DTNB to produce a yellow color [34] . The results demonstrated that among the extracts, the BuOH extract displayed the highest AChE enzyme inhibitor.…”

“…Acetylthiocholine iodide is hydrolyzed by the enzyme AChE to form thiocholine, which then reacts with DTNB to produce a yellow color. [34] The results demonstrated that among the extracts, the BuOH extract displayed the highest AChE enzyme inhibitor. The remaining extracts did not show any anti-AChE activity although they gave significant antioxidant activity.…”

“…The acetylcholinesterase (AChE) activity was assayed according to the Ellman colorimetric method [43] . The ATCI substrate is hydrolyzed by AChE to form thiocholine, which reacts with Ellman′s reagent (DTNB) to produce a yellow 5‐thio‐2‐nitrobenzoate anion [34] . The procedure was carried out by adding 1050 μl of phosphate buffer pH=8, 150 μl of the extracts (10–0.625 mg/mL), and 0.25 IU/ml AChE solution into the tubes.…”

“…[43] The ATCI substrate is hydrolyzed by AChE to form thiochowhich reacts with Ellman's reagent (DTNB) to produce a yellow 5-thio-2-nitrobenzoate anion. [34] The procedure was carried out by adding 1050 μl of phosphate buffer pH = 8, 150 μl of the extracts (10-0.625 mg/mL), and 0.25 IU/ml AChE solution into the tubes. The mixture of these solutions was mixed well and incubated for 15 min at room temperature.…”

Bioactive Diarylpentanoids: Insights into the Biological Effects beyond Antitumor Activity and Structure–Activity Relationships

“…The presence of an enone moiety between the two aromatic rings in the majority of these compounds makes them structurally related to chalcones, a well-known class of natural products with a wide range of biological activities [ 1 , 2 , 3 , 4 ]. Diarylpentanoids are also known as C5-curcuminoids since these are structurally related to curcumin (1 E ,6 E -17-bis(4-hydroxy-3-methoxyphenyl)hepta-16-diene-35-dione ( 1 : Figure 2 ), a C7-curcuminoid found in the traditional Indian herb Curcuma Longa [ 5 ]. This natural product ( 1 ) has shown diverse biological activities, such as antioxidant, antidiabetic, antimicrobial, antimalarial, antiviral, thrombosuppressive, antitumor, cardio- and neuro-protective properties, as well as chemopreventive activity [ 6 , 7 , 8 , 9 , 10 ] associated with different targets, which supports the idea that this compound influences a great variety of biochemical and molecular cascades [ 11 ].…”