Extraction of fucoxanthin, antioxidants and lipid from wet diatom Chaetoceros simplex var. calcitrans by liquefied dimethyl ether

Extraction and Separation of Natural Products from Microalgae and Other Natural Sources Using Liquefied Dimethyl Ether, a Green Solvent: A Review

“…The successful use of liquefied DME-based lipid extraction has been reported for several microalgae species, including Haematococcus pluvialis [168], Euglena gracilis [169,170], Aurantiochytrium limacinum [171], Arthrospira platensis [172], Chaetoceros gracilis, Pleurochrysis carterae [24], Monostroma nitidum [173], Tetradesmus obliquus [173], Nannochloropsis oculate [174], Phaeodactylum tricornutum [175], Haematococcus pluvialis [176], and various others [177,178]. These extractions resulted in high yields of specific oleaginous components and bio-oils, highlighting the efficacy of liquefied DME extraction.…”

“…Moreover, liquefied DME has been used to extract bioactive compounds from citrus leaves and peels (citrus flavonoids) [197], Garcinia mangostana Linn (mangostin) [198], vegetables (proteins) [199], lemon peel tissue (citric acid, vitamin C, and essential oils) [200], tuna liver (fish oil, n-3 polyunsaturated fatty acids) [201,202], macroalgae Monostroma nitidum (Lutein) [203], Japanese knotweed rhizomes (resveratrol and glycoside) [204], Centella asiatica leaves (triterpenoid) [205], hops (α-acids and β-acids) [206], cyanobacteria (fatty acids) [207], sugar mill waste (policosanol and phytosterol) [208], Curcuma longa L. (curcumin) [138], and diatom Chaetoceros simplex var. calcitrans (fucoxanthin) [178] (Figure 5). Most studies have indicated that liquefied DME exhibits a higher extraction rate than conventional extraction methods.…”