Extraction of phenolic compounds from Mentha aquatica: the effects of sonication time, temperature and drying method

Safaiee, Pedram; Taghipour, Amirhossein; Vahdatkhoram, Fatemeh; Movagharnejad, Kamyar

doi:10.1007/s11696-019-00843-5

Cited by 19 publications

(9 citation statements)

References 27 publications

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“…Freeze-dried M. aquatica leaves contained a higher TPC (0.25 mg/g) than the microwave-dried samples (0.17 mg/g), while the latter contained a higher TPC than the oven-dried leaves (0.12 mg/g) [129]. microwave oven drying ↑ TPC shortens drying time [127,128] direct sunlight drying at 20-30 • C ↑ TPC samples get polluted, time consuming [127] oven drying at 50 • C ↓ TPC not suitable for thermo-sensitive compounds [127] oven drying at 80 • C ↓ TPC time consuming [128] ↑ Content increased, ↓ Content decreased, 3 Total phenolic content.…”

Section: Variation In Phenolic Compositionmentioning

confidence: 81%

“…The methanol extracts of M. longifolia produced higher TPCs by ultrasonic extraction than the 70% aqueous ethanol extracts, while the later gave better TPCs by Soxhlet [ 124 ]. Freeze-dried M. aquatica leaves contained a higher TPC (0.25 mg/g) than the microwave-dried samples (0.17 mg/g), while the latter contained a higher TPC than the oven-dried leaves (0.12 mg/g) [ 129 ].…”

Section: Variation In Phenolic Compositionmentioning

confidence: 99%

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Potential Role of Phenolic Extracts of Mentha in Managing Oxidative Stress and Alzheimer’s Disease

et al. 2020

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With an increase in the longevity and thus the proportion of the elderly, especially in developed nations, there is a rise in pathological conditions that accompany ageing, such as neurodegenerative disorders. Alzheimer’s disease (AD) is a neurodegenerative disease characterized by progressive cognitive and memory decline. The pathophysiology of the disease is poorly understood, with several factors contributing to its development, such as oxidative stress, neuroinflammation, cholinergic neuronal apoptotic death, and the accumulation of abnormal proteins in the brain. Current medications are only palliative and cannot stop or reverse the progression of the disease. Recent clinical trials of synthetic compounds for the treatment of AD have failed because of their adverse effects or lack of efficacy. Thus, there is impetus behind the search for drugs from natural origins, in addition to the discovery of novel, conventional therapeutics. Mints have been used traditionally for conditions relevant to the central nervous system. Recent studies showed that mint extracts and/or their phenolic constituents have a neuroprotective potential and can target multiple events of AD. In this review, we provide evidence of the potential role of mint extracts and their derivatives as possible sources of treatments in managing AD. Some of the molecular pathways implicated in the development of AD are reviewed, with focus on apoptosis and some redox pathways, pointing to mechanisms that may be modulated for the treatment of AD, and the need for future research invoking knowledge of these pathways is highlighted.

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Section: Variation In Phenolic Compositionmentioning

confidence: 81%

Section: Variation In Phenolic Compositionmentioning

confidence: 99%

Potential Role of Phenolic Extracts of Mentha in Managing Oxidative Stress and Alzheimer’s Disease

et al. 2020

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“…By applying the absorbance values obtained from the plant extracts to the regression equation, the phenolic substance contents were expressed as µg gallic acid equivalent (GAE) (Table 1). freeze-drying method and they suggested that in FD samples, phenolics could be better preserved in the substrate [33].…”

Section: Resultsmentioning

confidence: 99%

Comparison of The Phenolic Content and Antioxidant Activity in Peppermint Plant According to The Drying Method

SALİHOĞLU

Şimşek

ÇAYIR

et al. 2022

Ankara Universitesi Eczacilik Fakultesi Dergisi

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Objective: Antioxidant activities of the plants were significantly affected by their drying methods. In the current study, total phenolic contents and antioxidant activity of aqueous extracts of peppermint (Mentha piperita L.) dried by two different methods, air-dried (AD) and freeze-dried (FD) were measured. The aim was to determine if there were any changes in the antioxidant activity according to the drying method.Material and Method: In order to determine the total phenolic compounds and antioxidant capacity of air-dried (AD) and freeze-dried (FD) mint, were used Folin Ciocalteu, CUPRAC, DPPH, ABTS, DMPD methods.Result and Discussion: Results were evaluated by comparing with the known antioxidant standards, such as gallic acid, trolox, ascorbic acid, and butylatedhydroxyanisole (BHA). The total phenolic contents (TPC) were calculated as 59.9 mg/g GAE for AD plant extract and 58.2 mg/g GAE for FD extract. According to the obtained results from all methods, radical scavenging activities were found to be slightly higher in AD samples than in FD samples. In conclusion, the results show that air-drying does not cause degradation in compounds that contribute to the antioxidant activity of the peppermint.

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“…The extracts showed the same molecules (ellagic acid, hyperoside, rutin, and epicatechin) as those found in fresh tepals by Caser et al [ 15 ] using an analysis protocol similar to this study. In addition, in the dried tepals were also detected ferulic acid, isoquercitrin, quercitrin, and vitamin C. In Caser et al [ 15 ] the absence in fresh tepals of the chemicals here obtained might be attributed to the drying procedure [ 61 , 62 ], which can facilitate extractions by disrupting cell walls and causing the formation of cavities and intercellular spaces [ 63 ]. Vitamin C and rutin (yield up to 37.61 ± 2.22 mg 100 g −1 DW) showed the highest yields among all the compounds analyzed with HPLC.…”

Section: Discussionmentioning

confidence: 99%

Sustainable Processing of Floral Bio-Residues of Saffron (Crocus sativus L.) for Valuable Biorefinery Products

Stelluti

Caser

Demasi

et al. 2021

Plants

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Tepals constitute the most abundant bio-residues of saffron (Crocus sativus L.). As they are a natural source of polyphenols with antioxidant properties, they could be processed to generate valuable biorefinery products for applications in the pharmaceutical, cosmetic, and food industries, becoming a new source of income while reducing bio-waste. Proper storage of by-products is important in biorefining and dehydration is widely used in the herb sector, especially for highly perishable harvested flowers. This study aimed to deepen the phytochemical composition of dried saffron tepals and to investigate whether this was influenced by the extraction technique. In particular, the conventional maceration was compared with the Ultrasound Assisted Extraction (UAE), using different solvents (water and three methanol concentrations, i.e., 20%, 50%, and 80%). Compared to the spice, the dried saffron tepals showed a lower content of total phenolics (average value 1127.94 ± 32.34 mg GAE 100 g−1 DW) and anthocyanins (up to 413.30 ± 137.16 mg G3G 100 g−1 DW), but a higher antioxidant activity, which was measured through the FRAP, ABTS, and DPPH assays. The HPLC-DAD analysis detected some phenolic compounds (i.e., ferulic acid, isoquercitrin, and quercitrin) not previously found in fresh saffron tepals. Vitamin C, already discovered in the spice, was interestingly detected also in dried tepals. Regarding the extraction technique, in most cases, UAE with safer solvents (i.e., water or low percentage of methanol) showed results of phenolic compounds and vitamin C similar to maceration, allowing an improvement in extractions by halving the time. Thus, this study demonstrated that saffron tepals can be dried maintaining their quality and that green extractions can be adopted to obtain high yields of valuable antioxidant phytochemicals, meeting the requirement for a sustainable biorefining.

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Extraction of phenolic compounds from Mentha aquatica: the effects of sonication time, temperature and drying method

Cited by 19 publications

References 27 publications

Potential Role of Phenolic Extracts of Mentha in Managing Oxidative Stress and Alzheimer’s Disease

Potential Role of Phenolic Extracts of Mentha in Managing Oxidative Stress and Alzheimer’s Disease

Comparison of The Phenolic Content and Antioxidant Activity in Peppermint Plant According to The Drying Method

Sustainable Processing of Floral Bio-Residues of Saffron (Crocus sativus L.) for Valuable Biorefinery Products

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