Extraction optimization by using response surface methodology and purification of yellow pigment from <i>Gardenia jasminoides</i> var. <i>radicans</i> Makikno

Wu, Jun; Zhang, Jiangtao; Xin, Yu; Shu, Yang; Zhang, Siyu; Zhang, Yinglao

doi:10.1002/fsn3.2046

Cited by 15 publications

(5 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This may play the same role or provide new guidance in obtaining more Gardenia yellow pigment from G. jasminoides var. radicans Makikno ( Wu et al., 2020 ), extracting flavonoids from flowers ( Mlcek et al., 2021 ), and using myricetin and kaempferol as anticancer substances ( Rahmani et al., 2023 ).…”

Section: Discussionmentioning

confidence: 99%

Transcriptome and metabolome analysis reveals the effect of flavonoids on flower color variation in Dendrobium nobile Lindl.

Qiu,

Cai,

et al. 2023

Front. Plant Sci.

View full text Add to dashboard Cite

IntroductionDendrobium nobile L. is a rare orchid plant with high medicinal and ornamentalvalue, and extremely few genetic species resources are remaining in nature. In the normal purple flower population, a type of population material with a white flower variation phenotype has been discovered, and through pigment component determination, flavonoids were preliminarily found to be the main reason for the variation.MethodsThis study mainly explored the different genes and metabolites at different flowering stages and analysed the flower color variation mechanism through transcriptome- and flavonoid-targeted metabolomics. The experimental materials consisted of two different flower color phenotypes, purple flower (PF) and white flower (WF), observed during three different periods.Results and discussionThe results identified 1382, 2421 and 989 differentially expressed genes (DEGs) in the white flower variety compared with the purple flower variety at S1 (bud stage), S2 (chromogenic stage) and S3 (flowering stage), respectively. Among these, 27 genes enriched in the ko00941, ko00942, ko00943 and ko00944 pathways were screened as potential functional genes affecting flavonoid synthesis and flower color. Further analysis revealed that 15 genes are potential functional genes that lead to flavonoid changes and flower color variations. The metabolomics results at S3 found 129 differentially accumulated metabolites (DAMs), which included 8 anthocyanin metabolites, all of which (with the exception of delphinidin-3-o-(2’’’-o-malonyl) sophoroside-5-o-glucoside) were found at lower amounts in the WF variety compared with the PF variety, indicating that a decrease in the anthocyanin content was the main reason for the inability to form purple flowers. Therefore, the changes in 19 flavone and 62 flavonol metabolites were considered the main reasons for the formation of white flowers. In this study, valuable materials responsible for flower color variation in D. nobile were identified and further analyzed the main pathways and potential genes affecting changes in flavonoids and the flower color. This study provides a material basis and theoretical support for the hybridization and molecular-assisted breeding of D. nobile.

show abstract

Section: Discussionmentioning

confidence: 99%

Transcriptome and metabolome analysis reveals the effect of flavonoids on flower color variation in Dendrobium nobile Lindl.

Qiu,

Cai,

et al. 2023

Front. Plant Sci.

View full text Add to dashboard Cite

show abstract

“…Before designing the response surface parameter, single-factor experiments were carried out to decide the appropriate range of various factors [27]. The ranges of independent variables were as follows: ratios of H 2 O to β-CD (5:1, 10:1, 15:1, 20:1, 25:1 mL/g), stirring time (0.5, 1, 1.5, 2, 2.5 h), ratios of β-CD to CLEO (4:1, 6:1, 8:1, 10:1, 12:1 g/mL) and stirring temperature (20,30,40,50, 60 • C) [28].…”

Section: The Response Surface Methodology 241 Single-factor Experimentsmentioning

confidence: 99%

Preparation, Optimization, and Characterization of Inclusion Complexes of Cinnamomum longepaniculatum Essential Oil in β-Cyclodextrin

et al. 2022

View full text Add to dashboard Cite

Cinnamomum longepaniculatum essential oil (CLEO) possesses antibacterial, anti-inflammatory, and antioxidant activities. However, CLEO shows volatilization and poor solubility, which limits its application field. In this research, inclusion complexes of β-cyclodextrin (β-CD) with CLEO were produced, and its physicochemical properties were characterized. Response surface methodology was used to obtain optimum preparation conditions. A statistical model was generated to define the interactions among the selected variables. Results show that the optimal conditions were an H2O/β-CD ratio of 9.6:1 and a β-CD/CLEO ratio of 8:1, with the stirring temperature of 20 °C for the maximal encapsulation efficiency values. The physicochemical properties of CLEO/β-CD inclusion complexes (CLEO/β-CD-IC) were investigated. Fourier transform infrared spectroscopy showed that correlative characteristic bands of CLEO disappeared in the inclusion complex. X-ray diffraction presented different sharp peaks at the diffraction angle of CLEO/β-CD-IC. The thermogravimetric analysis demonstrated the thermal stability of CLEO was enhanced after encapsulation. Tiny aggregates with a smaller size of CLEO/β-CD-IC particles were observed by scanning electron microscopy. The comparison of β-CD, CLEO, and physical mixtures with CLEO/β-CD-IC confirmed the formation of inclusion complexes.

show abstract

“…The type of solvent or solvent-plant sample ratio also has great significance, and such analysis can indeed help to avoid the overuse of the solvents (Azwanida 2015). For example, in the case of the classical extraction of antioxidants from rosemary (Oliveira et al 2016) or gardenia fruit (Wu et al 2021) solvent-plant ratio was the factor of the greatest influence on the response.…”

Section: Critical Aspects and Concluding Remarksmentioning

confidence: 99%

Optimization of food-grade bioactive compound extraction from plant sources by response surface methodology approach: A comprehensive review

Karabegoić,

Stojanović,

Mančić

et al. 2023

Maso International – Journal of Food Science and Technology

View full text Add to dashboard Cite

This comprehensive review delves into the extensive application of response surface methodology (RSM), a prominent mathematical and statistical technique, for modeling and optimizing the extraction of food-grade bioactive compounds from plant sources. The paper elucidates the optimization approach, covering experimental design, empirical models for response prediction, and the utilization of the desirability function for multiple response optimization. RSM provides a contemporary means to concurrently analyze and optimize various factors, presenting mathematical models for enhancing extraction processes efficiently. The review showcases RSM applications in traditional extraction techniques such as classical solvent extraction, Soxhlet extraction, and hydrodistillation, with a focus on factors like extraction time, temperature, ratio of plant material to solvent, and solvent concentration. The economic feasibility of RSM-optimized extraction processes is discussed, encompassing considerations of processing time, solvent consumption, and overall cost reduction. Critical aspects and challenges related to RSM implementation in extraction optimization are addressed, underscoring the significance of appropriate experimental design, model accuracy, and the incorporation of multiple responses for comprehensive optimization. The review concludes by emphasizing the pivotal role of RSM in guiding rational and efficient extraction processes for various valuable natural compounds from plant materials.

show abstract

Extraction optimization by using response surface methodology and purification of yellow pigment from Gardenia jasminoides var. radicans Makikno

Cited by 15 publications

References 38 publications

Transcriptome and metabolome analysis reveals the effect of flavonoids on flower color variation in Dendrobium nobile Lindl.

Transcriptome and metabolome analysis reveals the effect of flavonoids on flower color variation in Dendrobium nobile Lindl.

Preparation, Optimization, and Characterization of Inclusion Complexes of Cinnamomum longepaniculatum Essential Oil in β-Cyclodextrin

Optimization of food-grade bioactive compound extraction from plant sources by response surface methodology approach: A comprehensive review

Contact Info

Product

Resources

About