Extraction, purification, structural features, modifications, bioactivities, structure–activity relationships, and applications of polysaccharides from garlic: A review

Zhang, Yongwei; Li, Lanlan; Ma, Xuehong; Liu, Ruiting; Shi, Rongmei; Zhao, Dongsheng; Li, Xinxia

doi:10.1016/j.ijbiomac.2024.131165

International Journal of Biological Macromolecules

2024

DOI: 10.1016/j.ijbiomac.2024.131165

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Extraction, purification, structural features, modifications, bioactivities, structure–activity relationships, and applications of polysaccharides from garlic: A review

Yongwei Zhang,

Lanlan Li,

Xuehong Ma

et al.

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2024

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Cited by 2 publications

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A soluble garlic polysaccharide supplement alleviates fatigue in mice

Li,

Xie,

Tian

et al. 2024

npj Sci Food

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A soluble garlic polysaccharide supplement alleviates fatigue in mice

Li,

Xie,

Tian

et al. 2024

npj Sci Food

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Extraction, purification, structural characterization, bioactivities, modifications and structure–activity relationship of polysaccharides from Ophiopogon japonicus: a review

Zhang,

Chen,

Zhang

et al. 2024

Front. Nutr.

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Ophiopogon japonicus (Thunb.) Ker Gawl., is a traditional Chinese medicine (TCM) with a history of thousands of years. O. japonicus polysaccharides (OJPs), as one of the main active ingredient, are a kind of representative pharmacological bioactive macromolecules and mainly composed of Glc and Fru with molecular weight between 2.48 and 325 kDa. OJPs have a variety of biological activities, such as hypoglycemic, cardioprotective, immunomodulatory, improvement of obesity, and renal protective activity. In this review, the extraction, purification and structural characterization of OJPs were systematically reviewed, and its biological function, molecular mechanism and structure–activity relationship were analyzed. Additionally, this review summarized and found that structural modifications such as liposome modification, sulfation modification, and polyethylene glycol modification have improved the pharmacological activity and bioavailability of OJPs. Overall, this work will help to better understand OJPs and provide a theoretical review of their further development and utilization in the field of medicine and health food.

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Extraction, purification, structural features, modifications, bioactivities, structure–activity relationships, and applications of polysaccharides from garlic: A review

Cited by 2 publications

References 99 publications

A soluble garlic polysaccharide supplement alleviates fatigue in mice

A soluble garlic polysaccharide supplement alleviates fatigue in mice

Extraction, purification, structural characterization, bioactivities, modifications and structure–activity relationship of polysaccharides from Ophiopogon japonicus: a review

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