Extraction, Qualitative and Quantitative Determination of Secondary Metabolites of Rumex Nepalensis Roots

Khan, Azher Nawaz; Bhat, Irm

doi:10.22270/jddt.v8i6-s.2092

Cited by 10 publications

(4 citation statements)

References 6 publications

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“…A higher fidelity level is considered as a clue for the high healing potential of these plants against the corresponding diseases. Secondary metabolites with wound healing effects were previously reported from Rumex nepalensis by [ 47 , 48 ]. This might be the reason why local people use the species widely to treat wounds.…”

Section: Resultsmentioning

confidence: 95%

Traditional lore on the healing effects of therapeutic plants used by the local communities around Simien Mountains National Park, northwestern Ethiopia

Seraw,

Melkamu,

Masresha

2024

J Ethnobiology Ethnomedicine

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Background Simien Mountain National Park is a world heritage site with spectacular landscapes and rich in floral diversity. Exploring the plethora of conventional wisdom regarding therapeutic flora for sustainable use and drug development is a timely endeavor. Thus, the present study was aimed at investigating therapeutic plant uses and conservation practices by the local communities dwelling in the vicinity of the Park. Methods Eighty randomly selected general informants and 20 purposefully selected key informants were used to collect the traditional lore from 10 purposefully selected kebeles that border the Park. Data were collected using face-to-face interviews, guided field walks, group discussions and market surveys. Descriptive statistics were used to analyze the basic information collected from the informants. An independent sample t test was computed to compare the knowledge variations among different informant groups. Clustering and ranking techniques were employed to validate traditional wisdom of informants. Results Significant differences in traditional wisdom (P < 0.05) were observed only between general and key informants. Hundred thirteen therapeutic plant species belonging to 56 families were recorded. Asteraceae was the most species-rich family (10%). The majority of therapeutic species were collected from the wild (77%). Herbs and roots were the most preferred habit (47%) and plant parts (37%) for remedy preparation, respectively. Pounding was the most common preparation method (50.1%). The most frequently practiced route of administration was the oral route (48.1%). The highest Informant Consensus Factor (ICF) value (84%) was recorded for respiratory and febrile illnesses. Rumex nepalensis was the most preferred for the treatment of wounds, and Olea europaea subsp cuspidata was the first-ranked multipurpose plant. Conclusion The Park is rich in therapeutic species serving as a refuge for many endemic and endangered species associated with the local community rich medicinal traditional lore. Erosion of therapeutic plants, verbal transfer of the traditional wisdom and young generation negligence in acquiring traditional lore led to the deterioration of the long tradition of using therapeutic plants for health care. Endangered multipurpose therapeutic plants like Echinops kebericho should get conservation priority. Therapeutic plants with the highest ICF and fidelity level could be candidates for drug development.

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Section: Resultsmentioning

confidence: 95%

Traditional lore on the healing effects of therapeutic plants used by the local communities around Simien Mountains National Park, northwestern Ethiopia

Seraw,

Melkamu,

Masresha

2024

J Ethnobiology Ethnomedicine

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“…Then filtered, the extract mixture by using Whatman filter paper no.1 and centrifugation was done for 10 min at 5000 rpm. The supernatant was collected and stored in glass bottles for further use (Kanth et al ., 2019).…”

Section: Methodsmentioning

confidence: 99%

Green synthesis of copper nanoparticles fromNigella sativaseed extract and evaluation of their antibacterial and antiobesity activity

Kumar

Kaushik

Kumar

et al. 2023

Int J of Food Sci Tech

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In this study, the copper nanoparticles were synthesized using various concentrations (5%, 6 %, 8%, and 10%) of Nigella sativa seed extracts, and their antibacterial and antiobesity effect was evaluated. The optimum particle size (98.23 nm) of nanoparticles was obtained at an extract concentration of 8%. FTIR results confirmed the functional groups responsible for copper ion reduction, The synthesized nanoparticles exhibited high antibacterial activity against Pseudomonas aeruginosa and Escherichia coli having inhibition zone of 25 mm and 24 mm, respectively. Significantly (P < 0.005) percent lipase and amylase inhibition assay of copper nanoparticles confirmed their antiobesity activities.

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“…The total phenols in different solvent extracts of A. chinense leaf were evaluated using FC (Folin-Ciocalteu) spectrophotometric method (Khan and Bhat, 2018). The standard curve was plotted using gallic acid at 1-100 µg/ml concentrations.…”

Section: Determination Of Total Phenolsmentioning

confidence: 99%

GC-MS based metabolite profiling and antioxidant activity of solvent extracts of Allium chinense G Don leaves

et al. 2021

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Allium chinense, a main source of “Xiebai” drug in Chinese traditional medicine and commonly known as Ganoderma lucidum belongs to the family Amaryllidaceae. The main focus of this research was to quantify the secondary metabolites, antioxidant potential and study the GC- MS based metabolite profile of different solvent leaf extracts of A. chinense. The reports on the bioactive compounds of A. chinense leaves are still insufficient compared to the bulb; hence this study was carried out to understand the bioactive compounds present in A. chinense leaves using different solvents of varying polarity. Our investigation showed that the ethanol extract contained the highest saponin, flavonoid, phenol, and DPPH scavenging activity. Further, metabolite profiling revealed a total of forty-eight compounds, indicating a diverse range of phytochemicals present in the four extracts. The highest number of compounds were observed in ethanol extract (15) followed by chloroform extract (13), petroleum ether extract (11) and methanol extract (9). Some of the major compounds identified in the four solvents are octacosane (27.11%), heptadecane (19.66%), eicosane (18.51%), ethyl palmitate (18.50%), phytol (17.68%) and phytol acetate (17.30%). In conclusion, this study highlights that A. chinense leaf extracts contain high saponins, terpenes and alkanes which could be a potential source of a new beneficial drug.

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Extraction, Qualitative and Quantitative Determination of Secondary Metabolites of Rumex Nepalensis Roots

Cited by 10 publications

References 6 publications

Traditional lore on the healing effects of therapeutic plants used by the local communities around Simien Mountains National Park, northwestern Ethiopia

Traditional lore on the healing effects of therapeutic plants used by the local communities around Simien Mountains National Park, northwestern Ethiopia

Green synthesis of copper nanoparticles fromNigella sativaseed extract and evaluation of their antibacterial and antiobesity activity

GC-MS based metabolite profiling and antioxidant activity of solvent extracts of Allium chinense G Don leaves

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