Extraction the Dayak Onion (Eleutherine sp): Scientific Based Herbal Medicine (OHT) Production Protocol

Abstract

Indonesia has the second largest tropical forest and the richest in flora biodiversity in the world. Based on the Basic Health Research 2010, 59.29% of Indonesian had consumed herbal medicine, noted that Indonesian had consumed herb since the VIII century. Dayak onion (Eleutherine sp) widely used as traditional medicine, as a bahimang /wound healing agent. Dayak onion is not reassured as a medical treatment and lacked scientific evidence. Until 2018, thousands of herbs consumed by Indonesian, only 85 ingredients clinically tested. Sixty-four herbs have been pre-clinically tested and designated as Scientific based Herbal Medicines/Obat Herbal Terstandar (OHT) and 21 herbs have been tested clinically and determined as Phytopharmaca by the Badan Pengawasan Obat dan Makanan Republik Indonesia (BPOM-RI). Based on the data, the Dayak onion appointed as a Scientific based Herbal medicine (OHT) based on pre-clinical and phase 0 clinical research. Potential and promising for the treatment of metabolic, degenerative, catastrophic, neoplasmic, genetic and infectious diseases, Dayak onions can be developed into phytopharmaca in the future. The study aim is to make guidelines for the standardized herbal medicines development according to the rules and regulations. Keywords: Dayak Onion, Eleutherine sp, Scientific based Herbal Medicines, Phytopharmaca, Pre Clinic and Clinical Trials phases

The effect of dayak onion (Eleutherine americana L. Merr) with cinnamon (Cinnamomum burmannii) and its application as an instant drink on fasting blood sugar levels in patients with type 2 diabetes mellitus

“…Giving an instant drink of Dayak onion syrup with cinnamon can reduce blood glucose levels in Type II Diabetes Mellitus clients and has been proven to be effective. This happens because the instant Dayak onion syrup drink with cinnamon reduces blood glucose levels and contains flavonoids which are natural organic compounds (Poerwosusanta, Ali, Noor, Mintaroem, & Widjajanto, 2018). The flavonoids contained can improve the performance of glucose metabolism and convert glucose into energy, this process can increase cell sensitivity to insulin so that glucose levels in the blood decrease (Badriyah, Agustina, & Elvierayani, 2021).…”

Dayak Onions (Eleutherine americana L Merr) Reduced Mesothelial Cell Detachment After Laparoscopy in Rats

“…The Dayak tribe has been utilizing Dayak onions (Eleutherine americana L. Merr) as a woundhealing remedy (bahimang) for centuries [7]. The major goal of the research was to show that Dayak onions can prevent mesothelial cell damage, and the secondary goal was to show that they had anti-inflammatory and antioxidant properties following laparoscopy.…”