Extractives of Decussocarpus wallichianus

Cambie, R. C.; Sidwell, David; Cheong, Chan Kai

doi:10.1021/np50033a041

Cited by 3 publications

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“…We also obtained and assigned the 13C-nmr spectrum of nagilactone G; this spectrum has not been published previously.Nagilactone E has only been isolated from Podocarpus nagi Zoll et Moritzi (5), while nagilactones F and G have been reported from several Podocarpus species (5-8).Within the genus Podocarpus sensu stricto, norditerpene dilactones, which exhibit interesting biological and pharmacological activity (9)(10)(11)(12)(13)(14), appear to be especially abundant (7). This fact suggests that the occurrence of similar compounds in D. rospigliosii could be important from the taxonomic and pharmacological point of view.The isolation of some phenolic diterpenes from Decussocarpus species (3,(15)(16)(17), which also occur in Podocarpus…”

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Norditerpene Dilactones from Decussocarpus rospigliosii

Amaro-Luis¹,

Carroz²

1988

J. Nat. Prod.

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Decussocarpus rospigliosii (Pilger) De Laubenfels (Podocarpaceae) is a tree found in Venezuela throughout the rain forest zone of the Andes (1). Taxonomically, this species had been included previously in the genus Podocarpus, but it eventually has been reclassified in the genus Decussocarpus (2).Recently, we reported the isolation and identification of four diterpenes in the phenolic fraction of the CHClj extract from the bark of the same species (3). We now report the isolation of nagilactone E, nagilactone F, nagilactone G, ß-sitosterol, and ß-sitosterol 3--ß-D-glucopyranoside from the neutral fraction of this extract.These compounds were identified by comparison of spectroscopic data with literature values (4-6). We also obtained and assigned the 13C-nmr spectrum of nagilactone G; this spectrum has not been published previously.Nagilactone E has only been isolated from Podocarpus nagi Zoll et Moritzi (5), while nagilactones F and G have been reported from several Podocarpus species (5-8).Within the genus Podocarpus sensu stricto, norditerpene dilactones, which exhibit interesting biological and pharmacological activity (9)(10)(11)(12)(13)(14), appear to be especially abundant (7). This fact suggests that the occurrence of similar compounds in D. rospigliosii could be important from the taxonomic and pharmacological point of view.The isolation of some phenolic diterpenes from Decussocarpus species (3,(15)(16)(17), which also occur in Podocarpus

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“…The isolation of some phenolic diterpenes from Decussocarpus species (3,(15)(16)(17), which also occur in Podocarpus…”

mentioning

confidence: 99%