Extradigital Glomus Tumor Mimics an Intrinsic Nerve Tumor in a Trauma Patient: Case Report and Literature Review

Ajala, Rodiyah T.; Lyon, Kristopher A.; Lyon, Priscilla R.; Harris, Franklin S.

doi:10.7759/cureus.19256

Cited by 3 publications

(25 citation statements)

References 17 publications

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“…Investigators summarized the features of eight patients who had an extradigital glomus tumor of their upper or lower extremities that was preceded by a history of local trauma. They found that injury occurred between two weeks to 21 years prior to the diagnosis of the tumor and that the types of injury included prior surgery (two patients), ruptured tendon repair (two patients), puncture from either a knife or tree (two patients), glass injury (one patient), and low-level trauma (one patient) [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

“…Indeed, especially for patients with very small tumors, the pain was often discordant with the size of the tumor. In addition, particularly in the setting of an extradigital glomus tumor, psychiatric misdiagnoses were assigned to some of those individuals whose lesion could not be clinically appreciated since it was either too small or too deeply located [ 8 , 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…Patients with a glomus tumor typically visit numerous physicians and healthcare professionals in an effort to discover the etiology of their painful lesion [ 4 ]. Indeed, one group of investigators commented that individuals with a glomus tumor experienced 2.5 consultations with a specialist prior to establishing the diagnosis [ 8 ]. The spectrum of clinicians who evaluated glomus tumor patients was extensive; in a study of 54 patients with an extradigital glomus tumor, encounters with the following individuals were recorded: acupuncturist, chiropractor, dermatologist, neurologist, neurosurgeon, orthopedist, primary care physician, and rheumatologist [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…Several of these conditions are also in the clinical differential diagnosis of an extradigital glomus tumor (Table 6 ) [ 2 , 3 , 5 , 6 , 8 , 9 , 11 , 15 ]. However, a retrospective study of 56 extradigital glomus tumors noted that hemangioma, neuroma, and neurofibroma were the most common misdiagnoses [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

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Glomus Extradigital Tumor: A Case Report of an Extradigital Glomus Tumor on the Wrist and Comprehensive Review of Glomus Tumors

Cohen¹

2023

Cureus

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A glomus tumor is a neoplasm composed of cells from the glomus body which is a contractile neuromyoarterial structure that affects blood pressure and thermoregulation by altering cutaneous blood flow. This cutaneous tumor can be benign or rarely malignant, solitary or multiple, and digital or extradigital. A benign glomus tumor usually presents as a non-familial, solitary, and subungual lesion. Multiple glomus tumors are less common, may be autosomal dominantly inherited, and extradigital. In contrast to a digital glomus tumor that often occurs within the nailbed or fingertip pulp of a young woman, a glomus extradigital tumor (GET) typically appears on the extremity or trunk of an older man. The diagnosis of a glomus tumor may be suspected based on clinical evaluation; it classically presents with a clinical triad of symptoms which includes lesion-associated tenderness, pin-point pressure pain, and cold sensitivity. However, cold-induced exacerbation of pain is frequently absent in extradigital glomus tumors; this may contribute to a delay in establishing the diagnosis of a glomus tumor in these individuals. Radiographic studies can support the diagnosis, but tissue specimen examination is necessary to establish the diagnosis. Resolution of tumor-associated pain is usually achieved following the complete excision of the neoplasm. A woman with a glomus tumor located on her wrist is described; her painful tumor was not sensitive to cold and was misdiagnosed clinically as a possible foreign body reaction to either a wood splinter or glass shard. The diagnosis of an extradigital glomus tumor was established after a microscopic examination of the tissue specimen following an excisional biopsy using a 3-millimeter punch biopsy tool. The neoplasm-related pain ceased and did not recur after the tumor had been completely removed. In conclusion, a glomus tumor is included in the differential diagnosis of a painful cutaneous neoplasm; however, misdiagnosis and/or substantial delay in diagnosis may occur if the tumor is extradigital or it lacks cold sensitivity or both. Therefore, the clinician needs to entertain the possibility of an extradigital glomus tumor when evaluating a patient with a tender, temperature-insensitive skin lesion that is not located on the fingers or toes.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Glomus Extradigital Tumor: A Case Report of an Extradigital Glomus Tumor on the Wrist and Comprehensive Review of Glomus Tumors

Cohen¹

2023

Cureus

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“…It usually arises in the distal extremities where glomus bodies are most abundant; however, it can grow anywhere in the body. As a result, it can present with variant localizing signs and symptoms, which makes the diagnosis challenging [ 3 , 4 ]. The malignant variant (glomangiosarcoma) is exceptionally uncommon, accounting for <1% of all glomus tumors [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

A case of malignant glomus tumor (glomangiosarcoma) of the nasal cavity

Alhroub¹,

Mahameed²,

Abdelhafez³

et al. 2022

Journal of Surgical Case Reports

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Glomus tumors are rare and usually benign. The malignant form (glomangiosarcoma) comprises <1% of all glomus tumors. There are limited reports that describe glomus tumors in the nasal cavity. However, to the best of our knowledge, glomangiosarcoma of the nasal cavity was never reported in humans. We report on the first case of nasal cavity glomangiosarcoma in a 59-year-old male who presented with a bleeding mass in his right nostril. We completely excised the lesion with a 0.7-mm free margin, and the histopathologic examination was consistent with glomangiosarcoma. A 6-month follow-up illustrated no evidence of recurrence or distant metastasis. Although it is rare, glomus tumors should be in the differential diagnosis of nasal cavity tumors. Histopathologic examination is essential for glomangiosarcoma diagnosis. Treatment requires complete excision with free margin, alongside careful clinical and radiological follow-up.

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A Case of Glomus Tumor of the Anterior Neck

Yamada,

Mitsukawa

2024

JPRS

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Extradigital Glomus Tumor Mimics an Intrinsic Nerve Tumor in a Trauma Patient: Case Report and Literature Review

Cited by 3 publications

References 17 publications

Glomus Extradigital Tumor: A Case Report of an Extradigital Glomus Tumor on the Wrist and Comprehensive Review of Glomus Tumors

Glomus Extradigital Tumor: A Case Report of an Extradigital Glomus Tumor on the Wrist and Comprehensive Review of Glomus Tumors

A case of malignant glomus tumor (glomangiosarcoma) of the nasal cavity

A Case of Glomus Tumor of the Anterior Neck

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