Extradural lumbar block with bupivacaine (Marcain: LAC‐43)

Bupivacaine

“…Bupivacaine, a homologue of mepivacaine, has been used in several clinical trials, particularly in Sweden where a markedly prolonged duration of effect has been shown in brachial plexus block (Hellman 1966) and in intercostal block (Telivuo 1963), whilst the extended duration in extradural block already noted abroad (Fortuna 1966, Korkeila 1966, Ekblom & Widman 1966 has recently been confirmed in trials in this country (Watt et al 1968, Steel & Dawkins 1968, Duthie etal. 1968).…”