Extragenital Bullous Lichen Sclerosus in a Pediatric Patient: A Case Report and Literature Review

Shiver, B S Mallory; Papasakelariou, Catherine; Brown, Jameel Ahmad; Wirges, Marla; Kincannon, Jay

doi:10.1111/pde.12025

Cited by 15 publications

(13 citation statements)

References 13 publications

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“…Haemorrhagic blisters in the setting of genital or extragenital lichen sclerosus have been described and it is known as bullous lichen sclerosus . In bullous areas we have observed haemorrhagic and orange homogeneous areas (Fig.…”

Section: Skin Conditions That Can Occasionally Be Orangementioning

confidence: 65%

Yellow and orange in cutaneous lesions: clinical and dermoscopic data

Bañuls

Arribas

Berbegal

et al. 2015

Acad Dermatol Venereol

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Colour of the lesions is clue for the clinical and dermoscopic diagnosis. Nevertheless, we have detected in the literature an uneven relevance of the colours as a diagnostic criterion. Thus, while red, brown and blue have taken important role in dermoscopic descriptions, other like yellow and orange have been given much less importance. This article reviews those lesions in which the yellow and orange colours have been considered constitutive or essential for diagnosis, and on the other hand it emphasizes the entities in which may appear these colours and are not well reflected in the literature. We believe that organize all this information will help us in a better understanding of these pathologies.

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Section: Skin Conditions That Can Occasionally Be Orangementioning

confidence: 65%

Yellow and orange in cutaneous lesions: clinical and dermoscopic data

Bañuls

Arribas

Berbegal

et al. 2015

Acad Dermatol Venereol

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“…Over time, lesions develop a porcelain white color, and a cigarette paper-like wrinkled appearance due to epidermal atrophy. Peripheral erythema, follicular keratotic plugs, telangiectasias, and hemorrhagic or non-hemorrhagic bullae may also be seen 8 .…”

Section: Discussionmentioning

confidence: 99%

“…There are a number of different treatment options and, there is no generally effective agent for LS. Various treatments including potent topical and intralesional steroids, psoralen with ultraviolet A therapy, long-wave ultraviolet A, low-dose ultraviolet A1, narrowband ultraviolet B, topical testosterone, estrogen, antimalarial agents, topical tacrolimus/pimecrolimus, topical retinoids, penicillin, vitamins, and surgical removal, have been used 8,11 . The cases of regression/remission of genital LS with treatment have been previously reported.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous regression of pediatric extragenital lichen sclerosus: A case report

Oğrum¹,

Dürer²

2019

TURKDERM

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©Copyright 2019 by Turkish Society of Dermatology and Venereology Turkderm-Turkish Archives of Dermatology and Venereology published by Galenos Yayınevi. Turkderm-Turk Arch Dermatol Venereology 2019;53:113-5 Liken sklerozus (LS) etiyolojisi bilinmeyen kronik enflamatuvar bir dermatozdur. Olguların büyük kısmı prepubertal ve perimenopozal dönemde olmakla beraber, hastalık her yaş grubunu etkileyebilir. Ağırlıklı olarak anogenital bölge etkilenmekte olup, ekstragenital tutulum çocuklukta nadir görülür. Anogenital lezyonlar klasik olarak kaşıntılı ve ağrılı beyaz ya da kırmızı yamalar şeklindeyken, ekstragenital lezyonlar sıklıkla asemptomatik beyaz papül ya da yamalar şeklindedir. Ekstragenital lezyonların en sık yerleştiği alanlar gövde, boyun ve aksilladır. Kızlardaki genital LS lezyonlarının çoğunluğu puberte döneminde spontan gerilerken, çocuklardaki ekstragenital LS lezyonlarının prognozuna ilişkin bilgi sınırlıdır. Burada, ekstragenital LS lezyonunda spontan regresyon görülen 14 yaşında bir kız olgu sunuldu.

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“…The recommended local therapy of LS is the application of super-potent topical glucocorticoids (clobethasol propionate), with or without topical calcineurin inhibitors, for long-term daily use. Some evidences support the use of pimecrolimus cream, or intralesion injection of triamcinolone 10 mg/mL for individual cases [4,10]. Firstly, our patient was treated with Cefazolin 6 g/daily, due to the impetiginization and inflammatory infiltration around the erosion, resulting from the bulla rupture.…”

Section: Discussionmentioning

confidence: 99%

Extragenital bullous and hemorrhagic Lichen sclerosus in a 58-year-old woman - A case report

Pavlov¹,

Nikiforova²,

Georgieva³

et al. 2017

Clin Case Rep Rev

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Lichen sclerosus (LS) is a rare, chronic, mucocutaneous disease, with a genital and extragenital manifestation. The etiology is not completely clarified, but there are suspicions for the role of genetic, autoimmune, infectious or hormonal factors.We present a 58-year-old woman with five-year evolution of rare bullous-hemorrhagic type of Lichen sclerosus, engaging the trunk and limbs and verified by histopathological examination. The disease was characterized by the appearance of hemorrhagic bullae on the sclero-atrophic plaques. The lesions were locally treated with high-potency topical corticosteroid (Clobetasol propionate 0.05% cream). A solution with antiseptic action (Povidone-iodine 10%) was administered for the erosion, caused by a rupture of the bulla. As a result, the erosion fully epithelized for a month. This case describes a rare type of Lichen sclerosus which responded favorably to the local treatment with corticosteroids and antiseptics.

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Extragenital Bullous Lichen Sclerosus in a Pediatric Patient: A Case Report and Literature Review

Cited by 15 publications

References 13 publications

Yellow and orange in cutaneous lesions: clinical and dermoscopic data

Yellow and orange in cutaneous lesions: clinical and dermoscopic data

Spontaneous regression of pediatric extragenital lichen sclerosus: A case report

Extragenital bullous and hemorrhagic Lichen sclerosus in a 58-year-old woman - A case report

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