Extragenital bullous lichen sclerosus on the anterior lower extremities: report of a case and literature review

Extragenital Bullous Lichen Sclerosus Treated with Fractional CO2 Laser (FxCO2) and Wet Dressing of Halcinonide Solution: A Case Report

“… 10 Extragenital bullous LS should be differentiated from bullous morphea, bullous lichen planus, cicatricial bullous pemphigoid, and circumscribed lymphangioma. 1 …”

“…Lichen sclerosus is a chronic inflammatory skin disease that typically presents as polygonal papules that coalesce into ivory-white sclerotic atrophic plaques. 1 The true incidence of LS is unknown and possibly underestimated due to providers’ lack of familiarity, asymptomatic presentations, or patient embarrassment. 2 Lichen sclerosus affects people of all ages.…”

“…In addition, an increased risk of squamous cell carcinoma has been reported in such patients. 1 Isolated extragenital lesions account for only 6% of LS. Unlike typical LS, the extragenital variant is prone to be asymptomatic and has no association with an increased risk of malignancy.…”

Painful and oozing bullous lesions in a 74‐year‐old woman

“…LSA and morphea may belong to the same disease spectrum 9 . For example, a case of a breast cancer patient with a radiation‐induced bullous morphea/LSA overlap has been described 10 .…”

“…The exact pathogenesis of LSA is still unknown, but multiple aetiologies are believed to exist 1,9 . Autoimmune and genetic influences are often mentioned 1,3,9 .…”