Extragenital lichen sclerosus with aetiological link to Borrelia

Vasudevan, Biju; Sagar, Amitabh; Bahal, Ashish; Mohanty, AP

doi:10.1016/s0377-1237(11)60089-0

Cited by 6 publications

(3 citation statements)

References 14 publications

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“…Multiple etiologic triggers such as drugs (statins, phenytoin), dietary supplements (l-tryptophan), infectious agents ( B. burgdorferi , Mycoplasma arginii ), vigorous physical exertion and trauma have been implicated, among others. [ 1 2 ] Our patient was a strict vegetarian who consumed dairy products and a liter of milk every day. Dairy products are a rich source of the amino acid tryptophan, that has been linked to EF.…”

Section: Discussionmentioning

confidence: 99%

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A rare case of unilateral eosinophilic fasciitis associated with ipsilateral extragenital lichen sclerosus

Sharma

Ray

Sridhar

et al. 2016

Indian Dermatol Online J

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Eosinophilic fasciitis, also known as Shulman's syndrome, is a fibrosing scleroderma-like syndrome, which is a distinct entity. A 55-year-old man, presented with progressive skin darkening, thickening, and tightening over the left lower limb since 6 months. Dermatological examination revealed a hyperpigmented indurated area on the left thigh, extending to the anterior aspect of the left leg. A well-defined hypopigmented indurated plaque was present over the left iliac region. Histopathology and imaging studies confirmed the diagnosis of eosinophilic fasciitis and lichen sclerosus. The indurated lesion on the left lower limb responded dramatically well to oral corticosteroids. This is a rare case of unilateral eosinophilic fasciitis associated with ipsilateral extragenital lichen sclerosus.

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Section: Discussionmentioning

confidence: 99%

“…Lichen sclerosus (LS), previously known as lichen sclerosus et atrophicus, is also a sclerosing inflammatory disorder of the dermis that affects the anogenital area in 85%–98% cases, with extragenital involvement in 15%–20% of patients. [ 1 ] Herein we report a rare case of unilateral EF with associated extragenital LS.…”

Section: Introductionmentioning

confidence: 99%

A rare case of unilateral eosinophilic fasciitis associated with ipsilateral extragenital lichen sclerosus

Sharma

Ray

Sridhar

et al. 2016

Indian Dermatol Online J

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“…[38] A case of extragenital lichen sclerosus with significant antibody titres to Borrelia has been reported previously. [39]…”

Section: Atypical Manifestationsmentioning

confidence: 99%

Lyme borreliosis and skin

Vasudevan

Chatterjee

2013

Indian J Dermatol

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Lyme disease is a multisystem illness which is caused by the strains of spirochete Borrelia burgdorferi sensu lato and transmitted by the tick, Ixodes. Though very commonly reported from the temperate regions of the world, the incidence has increased worldwide due to increasing travel and changing habitats of the vector. Few cases have been reported from the Indian subcontinent too. Skin manifestations are the earliest to occur, and diagnosing these lesions followed by appropriate treatment, can prevent complications of the disease, which are mainly neurological. The three main dermatological manifestations are erythema chronicum migrans, borrelial lymphocytoma and acrodermatitis chronica atrophicans. Many other dermatological conditions including morphea, lichen sclerosus and lately B cell lymphoma, have been attributed to the disease. Immunofluorescence and polymerase reaction tests have been developed to overcome the problems for diagnosis. Culture methods are also used for diagnosis. Treatment with Doxycycline is the mainstay of management, though prevention is of utmost importance. Vaccines against the condition are still not very successful. Hence, the importance of recognising the cutaneous manifestations early, to prevent systemic complications which can occur if left untreated, can be understood. This review highlights the cutaneous manifestations of Lyme borreliosis and its management.

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Lichen sclerosus: A C5B-9 mediated chronic microvascular injury syndrome potentially reflective of common adult comorbidities

Magro

Kalomeris

et al. 2023

Annals of Diagnostic Pathology

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Extragenital lichen sclerosus with aetiological link to Borrelia

Cited by 6 publications

References 14 publications

A rare case of unilateral eosinophilic fasciitis associated with ipsilateral extragenital lichen sclerosus

A rare case of unilateral eosinophilic fasciitis associated with ipsilateral extragenital lichen sclerosus

Lyme borreliosis and skin

Lichen sclerosus: A C5B-9 mediated chronic microvascular injury syndrome potentially reflective of common adult comorbidities

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