Extramammary Paget Disease in a Retrorectal Dermoid Cyst

Thway, Khin; Polson, Alexander; Pope, R. O.; Thomas, Joseph; Fisher, Cyril

doi:10.1097/pas.0b013e318158427b

Cited by 10 publications

(8 citation statements)

References 30 publications

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“…Within the abdomen and pelvis, the most common location is the sacrococcygeal region (Figure 2). These MCTs most frequently diagnosed in infancy, have an incidence of 1 per 30,000-43,000 live births 4 and are the most common teratomas of childhood accounting for 40% of those in the first two decades. 2 In adults, they occur most commonly in middle-aged females.…”

Section: Locationmentioning

confidence: 99%

“…2 In adults, they occur most commonly in middle-aged females. 4 Retroperitoneal MCTs (Figure 3) are also more common in childhood accounting for ,5% of all extragonadal GCTs. 1 They may cause considerable diagnostic confusion, if thought to represent Wilms' tumours or neuroblastomas.…”

Section: Locationmentioning

confidence: 99%

“…6 MALIGNANT TRANSFORMATION Malignant transformation in MCT is rare and reported to be between 1% and 12.5% for sacrococcygeal lesions. 4 The most common malignancies arising in teratomas are squamous carcinoma, carcinoid tumour and adenocarcinoma, 4 with neuroendocrine carcinoma and extramammary Paget's disease also rarely described. 4 Malignant change in MT is considered to be exceptionally rare.…”

Section: Locationmentioning

confidence: 99%

“…They may also contain fluid, fat and calcification in any combination (Figures 3b,c and 7a). The central cavity may contain hypoattenuating fluid ( Figure 7a) possibly with multiple low-attenuation spheres or "marbles" (Figure 2a), thought to consist non-dependent fat density keratin, 4 which may form secondary to hypovascularity. The floating spherules in this series are often poorly defined, and although of low attenuation do not demonstrate a consistently negative Hounsfield Unit as would typically be seen in fat, and are often poorly defined.…”

Section: Imagingmentioning

confidence: 99%

“…They contain tissue elements foreign to the organ or anatomic site of origin. 2 Arising from totipotent germ cells, they contain derivatives of one to all three germ cell layers (the ectoderm, endoderm and mesoderm) [2][3][4] and occur most frequently in the ovary or testis. Gonadal teratomas are well described; however, the extragonadal variants are under-represented in the literature.…”

mentioning

confidence: 99%

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Extragonadal teratomas of the adult abdomen and pelvis: a pictorial review

O'Donovan

Thway²,

Moskovic³

2014

BJR

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Teratomas comprise a spectrum of tumours that have striking imaging appearances and are commonly considered when evaluating a mass in the female pelvis. A subgroup of these tumours located in an extragonadal abdominopelvic location, in contrast, are extremely rare and can affect both sexes. Extragonadal teratomas can occur at all ages, are particularly unusual in adults and can cause confusion in the differential diagnosis, especially in children. Familiarity with the imaging features of the spectrum of teratomas within the abdominal cavity is therefore of great importance, as radiological diagnosis can guide treatment, prevent delays in diagnosis and avoid sequelae. This article summarizes the radiological appearances of these rare extragonadal tumours in adults in relation to their pathology, malignant potential, location and behaviour. Although uncommon, teratomas should be considered in the differential diagnosis of extragonadal abdominal masses, particularly in young adults.

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Section: Locationmentioning

confidence: 99%

Section: Locationmentioning

confidence: 99%