Extramammary Paget's disease arising in a mature cystic teratoma of the ovary: Immunohistochemical expression of androgen receptor

Ligand-independent androgen receptors promote ovarian teratocarcinoma cell growth by stimulating self-renewal of cancer stem/progenitor cells

“…Previous studies (Chadha et al, 1993;Cardillo et al, 1998;Shintaku et al, 2011) showed that 84% of benign and malignant ovarian tumors expressed AR; yet, there is no clear distinction between AR expression and ovarian cancers of different cellular origins. Because of the rarity of OVTC, few studies have been conducted on the pathogenesis of the disease.…”