Extramammary Paget's disease of scrotum—report of 25 cases and literature review

Extramammary Paget′s disease: Analysis of 17 Chinese cases

“…This male predominance (69-100%) is also reported in other Asian publications from China, Japan, and Korea. [8][9][10] Extramammary Paget's disease also appears to be much more common in Asia than previous reports about the occurrence in Caucasians would indicate. There are various possibilities to explain this difference: (1) Because of the large populations in Asia extramammary Paget's disease is more frequently seen in dermatology departments.…”

Successful treatment of recurrent extramammary Paget's disease of the penis and scrotum with imiquimod 5% cream

“…However, extensive resections are often followed by a high local rate of recurrence as invasion of the epidermis by Paget's cells often exceeds largely the visible limits of the lesions [1,3]. Thus, 32% to 50% of cases of male genital EMPD will recur after local resection [2].…”

“…Cases affecting the penis and scrotum are rare [1], as involvement of male genitalia is found in less than 14% of the cases [2]. Surgery with a 2 to 3 cm margin followed by reconstruction remains the mainstay of treatment [3]. However, recurrence rate remains high and surgery has often significant consequences for the functional anatomy with irreparable tissue damage.…”

Radiotherapy in Patients with Extramammary Paget's Disease - Our Own Experience and Review of the Literature

“…This data was collected by searching English-language journals included in the PubMed database and published between 1991 and 2012, using the keywords ‘EMPD' and ‘radiotherapy'. 15 available articles were identified [15,16,17,18,19,20,21,22,24,25,26,27,28,29,30]; however, 1 article [30] was excluded from this analysis because the applied radiotherapy methods were not described in detail. Therefore, 66 patients (21 male, 45 female; median age 73 years (range 38-92 years)) from 14 articles were analyzed (table 3).…”