Extramedullar Plasmacytoma

Abstract

Extramedullary plasmacytoma is a rare form of plasma cell dyscrasia, in which malignant plasma cell tumors arise outside the bone marrow. The tumor may arise in any part of the body but the vast majority occur in the head and neck, primarily in the nasal cavity, paranasal sinuses, or upper airway. Six patients with extramedullary plasmacytoma are presented and the clinical and radiographic findings are reviewed.

Sinonasal extramedullary plasmacytoma: a systematic review of 175 patients

“…All 67 studies included individual patient data that was extractable and fit the minimum criteria for inclusion. The 67 studies are detailed in Table …”

Intramuscular Extramedullary Plasmacytoma in Gluteus Medius Muscle: A Case Report and Literature Review

“…Plasmacytomas can occur in the absence of MM, or can be a complication of myeloma either at diagnosis or with disease progression. [4] When they occur alone, they are termed SP. SP is a plasma cell tumor without the features of disseminated myeloma.…”

“…A biopsy of the lesion, demonstrating plasma cell infiltration, is essential for confirming the diagnosis. [1][2][3][4][5][6] However, careful planning is required; Kansar et al described seeding of plasma cells in the tract following a percutaneous bone marrow biopsy. [22,23] The primary role of imaging is, therefore, to identify other lesions, local infiltration, and lymphadenopathy.…”

“…[3] Plasmacytomas are monoclonal plasma cell neoplasms that are one of the rare plasma cell neoplasms. [1][2][3][4][5] When they occur in the absence of MM, they are termed solitary plasmacytoma (SP) but can be associated with MM either at the time of diagnosis or with disease progression. SP can either occur in bone marrow or soft tissues (extramedullary).…”