Extramedullary hematopoiesis presenting as an asymptomatic posterior mediastinal mass: An unusual presentation

Takhar, Rajendra Prasad; Bunkar, Motilal; Jangid, Vinod Kumar; Saxena, Anil Kumar

doi:10.4103/0970-2113.188989

Cited by 8 publications

(11 citation statements)

References 5 publications

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“…Although the masses those are locating in the posterior mediastinum usually cause no symptoms, the ones with large dimensions might cause respiratory problems related to compression and neurologic deficits related to the level of involvement. The patients have complaints due to spontaneous pneumothorax, hemithorax and rapidly fatal respiratory failure [10,11,15]. Our case also had severe respiratory distress.…”

Section: Discussionmentioning

confidence: 88%

“…Some lesions are silent and waiting to be discovered by chance. Rare ones have signs of compressing neighboring organs [11,14,15]. EMH may rarely occur in unexpected places and as a lesion mimicking a tumor, forming a mass.…”

Section: Discussionmentioning

confidence: 99%

“…Symptoms related to mass formation seen in EMH cases are related to the location of the lesion [2,10]. Patients may sometimes be asymptomatic [2,11]. Although the masses those are locating in the posterior mediastinum usually cause no symptoms, the ones with large dimensions might cause respiratory problems related to compression and neurologic deficits related to the level of involvement.…”

Section: Discussionmentioning

confidence: 99%

“…The patients with EMH, are most commonly asymptomatic or have symptoms related to anemia such as fatigue and dizziness. Rarely, they occur as a solid mass and the patients have mass related symptoms [10,11]. The posterior mediastinum is an uncommon localization for EMH, except some sporadically reported intrathoracic manifestations.…”

Section: Introductionmentioning

confidence: 99%

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A mass-forming extramedullary hematopoiesis case mimicking mediastinal neoplasia

Uçak¹,

Ton²,

Temel³

et al. 2020

Curr Thorac Surg

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Extramedullary hematopoiesis (EMH) is a condition that usually coexists with hematological disorders and rarely causes mass formation. It can occur anywhere in the body, but very rarely becomes a tumorlike mass in the posterior mediastinum and paravertebral region. A 41-year-old female patient presented with respiratory distress. Radiologically, multiple large mass lesions were detected in the posterior mediastinum, localized bilaterally at paravertebral regions. Diagnostic studies with transthoracic biopsy specimen were showed that the mass lesion was consisting of myelocytes, lymphocytes, erythrocytes and megakaryocytes, so the case was reported as EMH. The case was presented to make a differential diagnosis, because it mimics solid neoplasms at unusual localizations, and may accompany hematological disorders.

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Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A mass-forming extramedullary hematopoiesis case mimicking mediastinal neoplasia

Uçak¹,

Ton²,

Temel³

et al. 2020

Curr Thorac Surg

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“…Surgical intervention is only required for EMH with complications including bleeding or compression of adjacent tissues. 6 EMH has been reported in association with various hematopoietic disorders and chronic anemia, but EMH without chronic anemia is a very rare condition and its clinical characteristics have not been fully understood.…”

Section: Introductionmentioning

confidence: 99%

Nonanemic extramedullary hematopoiesis in the posterior mediastinum

Nguyêñ

Nguyen

et al. 2018

Asian Cardiovasc Thorac Ann

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Extramedullary hematopoiesis is a rare condition characterized by the formation of blood cells outside the bone marrow. It is commonly seen in patients with hematopoietic disorders or chronic anemia. Here, we report the case of a 55-year-old patient who had extramedullary hematopoiesis that manifested as an asymptomatic posterior mediastinal mass. Chest computed tomography showed a 30 × 35-mm mass located on the left side of the D11 vertebra. Laboratory investigations revealed no signs of anemia. The tumor was safely and completely removed using video-assisted thoracoscopic surgery. Pathological studies confirmed the extramedullary hematopoiesis nature of the tumor.

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An intriguing case of a paravertebral extramedullary erythropoiesis presenting as tumor‐mimicking lesion in a patient with eosinophilia with FIP1L1‐PDGFRA rearrangement

Sassi

Houcine

Rahma

et al. 2022

Clinical Case Reports

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Extramedullary hematopoiesis presenting as an asymptomatic posterior mediastinal mass: An unusual presentation

Cited by 8 publications

References 5 publications

A mass-forming extramedullary hematopoiesis case mimicking mediastinal neoplasia

A mass-forming extramedullary hematopoiesis case mimicking mediastinal neoplasia

Nonanemic extramedullary hematopoiesis in the posterior mediastinum

An intriguing case of a paravertebral extramedullary erythropoiesis presenting as tumor‐mimicking lesion in a patient with eosinophilia with FIP1L1‐PDGFRA rearrangement

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