Extramedullary plasmacytoma arising from the lacrimal gland

Sia, David; Cannon, Paul S.; Selva, Dinesh

doi:10.1111/j.1442-9071.2010.02372.x

Cited by 2 publications

(1 citation statement)

References 13 publications

(34 reference statements)

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“…Orbital tumors are uncommon and often present with nonspecific findings mimicking the symptoms of dacryocystitis. EMP of the orbit is an even rarer entity with only a few cases reported to date [10]. Imaging features of EMPs are nonspecific.…”

Section: Discussionmentioning

confidence: 99%

Plasmacytoma of the Nasolacrimal Duct Simulating Dacryocystitis: An Uncommon Presentation for Extramedullary Relapse of Multiple Myeloma

Kalayoğlu-Beşışık¹,

Yonal²,

Hindilerden

et al. 2012

Case Rep Oncol

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The most common site for localized forms of plasma cell neoplasms (extramedullary plasmacytoma; EMP) is the upper respiratory tract, including the oropharynx, nasal cavities, sinuses and larynx. A 50-year-old woman with a history of myeloma in complete remission after autologous stem cell transplantation complained of two weeks of epiphora of the left eye with subsequent diplopia, bloody nasal discharge and progressive swelling around the nasolacrimal sac. A solitary mass in the left sinonasal area, extending to the nasolacrimal duct (NLD) was detected on MRI, whose histopathological examination was consistent with plasmacytoma. Further clinical investigation ruled out multiple myeloma (MM). The patient underwent debulking surgery and adjuvant chemotherapy followed by local radiotherapy in an attempt to achieve complete response. Despite being a rare entity, EMP of the NLD should be considered in the differential diagnosis of epiphora and dacryocystitis. To our knowledge, this is the first case of a plasmacytoma of the NLD presenting as isolated extramedullary relapse of MM. The follow-up in EMPs should include appropriate imaging studies, a systemic workup to rule out MM.

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Section: Discussionmentioning

confidence: 99%

Plasmacytoma of the Nasolacrimal Duct Simulating Dacryocystitis: An Uncommon Presentation for Extramedullary Relapse of Multiple Myeloma

Kalayoğlu-Beşışık¹,

Yonal²,

Hindilerden

et al. 2012

Case Rep Oncol

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Primary anaplastic extramedullary plasmacytoma in the lacrimal sac

Gupta,

Abhaypal,

Chatterjee

et al. 2024

Digit J Ophthalmol

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We report the case of a 60-year-old man diagnosed with unilateral, solitary, extramedullary plasmacytoma located in the right lacrimal sac fossa, with no systemic involvement. This rare plasma cell dyscrasia is usually found in the respiratory tract. Clinical and radiological features of the mass and histopathological results are described. The patient was successfully treated with complete surgical excision. There were no clinical or radiological indications of disease recurrence at 10 months’ follow-up.

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Extramedullary plasmacytoma arising from the lacrimal gland

Cited by 2 publications

References 13 publications

Plasmacytoma of the Nasolacrimal Duct Simulating Dacryocystitis: An Uncommon Presentation for Extramedullary Relapse of Multiple Myeloma

Plasmacytoma of the Nasolacrimal Duct Simulating Dacryocystitis: An Uncommon Presentation for Extramedullary Relapse of Multiple Myeloma

Primary anaplastic extramedullary plasmacytoma in the lacrimal sac

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