Extraocular sebaceous carcinoma as a rapidly growing back mass: a case report

Lipman, Kelsey; Franck, Philipp; Brownstone, Nicholas; Ascherman, Jeffrey A.

doi:10.5070/d32611047674

Cited by 5 publications

(11 citation statements)

References 22 publications

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“…Extraocular sebaceous carcinoma frequently arises from the skin of the head and neck, corresponding to the density of sebaceous glands [ 1 , 2 ]. Though uncommon, cases like the one we report here have been reported in additional anatomical locations, including the trunk, genitals, extremities, and breast [ 6 - 8 ].…”

Section: Discussionmentioning

confidence: 82%

Sebaceous Carcinoma of the Wrist in an Elderly Woman: A Case Report

Reddy,

Purser,

Nelson

et al. 2023

Cureus

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Sebaceous carcinoma is a rare, aggressive cutaneous malignancy most commonly arising from the periocular area. Extraocular locations of sebaceous carcinomas, particularly outside of the head and neck region, are rare and not well-described. We report a case of an 89-year-old Caucasian female with sebaceous carcinoma of the right wrist. She initially presented with a 1.2-centimeter friable nodule on the right wrist. Initial shave biopsy and subsequent pathologic evaluation revealed a basaloid neoplasm with sebaceous differentiation, atypia, and frequent mitoses, consistent with sebaceous carcinoma. The presented case reviews common clinical features and the pertinent histopathology of ocular and extraocular sebaceous carcinoma and provides a literature review of diagnosis, prognosis, and treatment.

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Section: Discussionmentioning

confidence: 82%

Sebaceous Carcinoma of the Wrist in an Elderly Woman: A Case Report

Reddy,

Purser,

Nelson

et al. 2023

Cureus

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“…Although 5 mm margins were employed and verified as negative during excision, the specific application of margin sizes to prevent recurrence remains a subject with limited consensus in the medical literature. Generally, 5-6 mm margins or up to 1 cm are considered standard [ 11 ]. Also, there are no distinct guidelines concerning systemic evaluation; however, those with large tumors or longstanding tumors may benefit from imaging with CT or MRI to check for metastasis.…”

Section: Discussionmentioning

confidence: 99%

Extra-Ocular Sebaceous Carcinoma Unveiled: A Case Study of Dermal Challenges in an Elderly African American Patient

Pearl,

Zielinski,

Zaragoza

2024

Cureus

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Sebaceous carcinoma is a rare malignant tumor of the sebaceous glands that most commonly presents in the periocular area. Uncommon extraocular manifestations are occasionally observed, often limited to the head or neck but can occur wherever sebaceous glands are found. There are increasing cases of sebaceous carcinoma in the United States which continue to pose ongoing diagnostic challenges. We present a patient with a 5.5 x 4 x 2 cm gradually growing necrotic and fungating upper back mass, present for one year. This lesion was initially diagnosed as an excoriated sebaceous adenoma, microscopically showing well-formed organoid structures and no irregular infiltration into the dermis, but was later confirmed as sebaceous carcinoma, demonstrating prominent mitosis and infiltrative growth pattern, following wide surgical excision. Margins were clear following the surgery with no signs of recurrence but further treatment recommendations included follow-up with oncology due to the rarity and aggressive nature of this tumor. This case serves to present an atypical presentation of a rare malignancy that has an increased occurrence rate for unknown reasons.

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“…In advanced stages, it may involve the conjunctiva, cornea, orbital and periorbital structures [10,11]. Extraocular sebaceous carcinoma accounts for 25% of cases [1,12]. The pathogen-nego bezpośredniego z otoczenia owrzodzenia na brzuchu oraz ze zmiany w obrębie skóry brzucha w celu oceny histologicznej.…”

Section: Discussionunclassified

“…There are sporadic reports of cases where the cancer has developed outside the skin in organs such as the nipple, ovary, prostate or parotid gland [14]. Although most publications describe extraocular cancer as a small, slow-growing hard, painless, yellowish to reddish-brown ulcerated tubercle [1,7,11,15,16], sometimes the course of the disease can be dynamic, as in in the case presented by us [12,17].…”

Section: Discussionmentioning

confidence: 99%

Extraocular form of sebaceous carcinoma with an aggressive course

Kucharczyk,

Dziurzyńska,

Błaszczyk

et al. 2023

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Introduction: Sebaceous carcinoma is a rare, usually slow-growing, malignant epithelial tumor of the skin. Mostly located on the face and neck, especially on the upper eyelid. It accounts for less than 1% of all skin malignancies. Extraocular sebaceous carcinoma is a very rare variant of this cancer. Case report: This paper presents a case of a 92-year-old man who presented with extensive, rapidly growing ulceration, located on the chest and abdomen. Based on the results of histopathological examinations and specific immunohistochemical staining, advanced sebaceous carcinoma was diagnosed in the thoracic and abdominal region. Conclusions: In patients with rapidly spreading ulcers, sebaceous carcinoma should also be considered in the differential diagnosis, although the course of this tumor is usually slow.

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Extraocular sebaceous carcinoma as a rapidly growing back mass: a case report

Cited by 5 publications

References 22 publications

Sebaceous Carcinoma of the Wrist in an Elderly Woman: A Case Report

Sebaceous Carcinoma of the Wrist in an Elderly Woman: A Case Report

Extra-Ocular Sebaceous Carcinoma Unveiled: A Case Study of Dermal Challenges in an Elderly African American Patient

Extraocular form of sebaceous carcinoma with an aggressive course

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